Table of contents

Report

Group: paint - Dataset: paint_goa_human

SUMMARY

This report generated on 2024-04-19

Header From Original Association File

!gaf-version: 2.2
!Created on Tue Feb 13 09:38:49 2024.
!generated-by: PANTHER
!date-generated: 2024-02-13
!PANTHER version: v.17.0.
!GO version: 2024-01-17.

Contents

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other

MESSAGES

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No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'

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IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

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IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC

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IPI should not be used with GO:0003824 catalytic activity or descendents

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No annotations should be made to uninformative high level terms

Messages

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ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

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Taxon-appropriate annotation check

Messages

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Dual species taxon check

gorule-0000016

With/From: IC annotations require a With/From GO ID

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IDA annotations must not have a With/From entry

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IPI annotations require a With/From entry

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

Messages

gorule-0000028

GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect

gorule-0000029

IEAs should be less than one year old.

gorule-0000030

Obsolete GO_REFs are not allowed

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IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference

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Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

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Qualifier: IKR evidence code requires a NOT qualifier

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Check for valid combination of evidence code and GO_REF

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The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

Messages

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Annotations to ISS, ISA and ISO should not be self-referential

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References should have only one ID per ID space

gorule-0000058

Object extensions should conform to the extensions-patterns.yaml file in metadata

gorule-0000061

Allowed gene product to term relations (gp2term)

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Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)

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TreeGrafter IEAs should be filtered for GO reference species

other

Predictions

GO:0070098 chemokine-mediated signaling pathway AnnotationPropagation P GO:0016493 C-C chemokine receptor activity IBA
GO:0045202 synapse AnnotationPropagation C GO:0007268 chemical synaptic transmission IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042800 histone H3K4 methyltransferase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G protein-coupled photoreceptor activity IBA
GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G protein-coupled photoreceptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0016209 antioxidant activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015267 channel activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016192 vesicle-mediated transport AnnotationPropagation P GO:0035615 clathrin adaptor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0030368 interleukin-17 receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005262 calcium channel activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0045202 synapse AnnotationPropagation C GO:0007268 chemical synaptic transmission IBA
GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0004896 cytokine receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042054 histone methyltransferase activity IBA
GO:0045892 negative regulation of DNA-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0008083 growth factor activity IBA
GO:0045892 negative regulation of DNA-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0034498 early endosome to Golgi transport IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0072320 volume-sensitive chloride channel activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042800 histone H3K4 methyltransferase activity IBA
GO:0098656 monoatomic anion transmembrane transport AnnotationPropagation P GO:0008308 voltage-gated monoatomic anion channel activity IBA
GO:0034204 lipid translocation AnnotationPropagation P GO:0140326 ATPase-coupled intramembrane lipid transporter activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0008528 G protein-coupled peptide receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0048013 ephrin receptor signaling pathway AnnotationPropagation P GO:0005005 transmembrane-ephrin receptor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004980 melanocyte-stimulating hormone receptor activity IBA
GO:0036066 protein O-linked fucosylation AnnotationPropagation P GO:0046922 peptide-O-fucosyltransferase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0006264 mitochondrial DNA replication IBA
GO:0005773 vacuole AnnotationPropagation C GO:0006624 vacuolar protein processing IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0004879 nuclear receptor activity IBA
GO:0030522 intracellular receptor signaling pathway AnnotationPropagation P GO:0004879 nuclear receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0045125 bioactive lipid receptor activity IBA
GO:0045892 negative regulation of DNA-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0017148 negative regulation of translation AnnotationPropagation P GO:0030371 translation repressor activity IBA
GO:0071897 DNA biosynthetic process AnnotationPropagation P GO:0003887 DNA-directed DNA polymerase activity IBA
GO:0034204 lipid translocation AnnotationPropagation P GO:0140326 ATPase-coupled intramembrane lipid transporter activity IBA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0004601 peroxidase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0045202 synapse AnnotationPropagation C GO:0007268 chemical synaptic transmission IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034551 mitochondrial respiratory chain complex III assembly IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0046961 proton-transporting ATPase activity, rotational mechanism IBA
GO:0034204 lipid translocation AnnotationPropagation P GO:0140326 ATPase-coupled intramembrane lipid transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0006390 mitochondrial transcription IBA
GO:0032508 DNA duplex unwinding AnnotationPropagation P GO:0009378 four-way junction helicase activity IBA
GO:0050918 positive chemotaxis AnnotationPropagation P GO:0042056 chemoattractant activity IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0042056 chemoattractant activity IBA
GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0004896 cytokine receptor activity IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0005125 cytokine activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0034220 monoatomic ion transmembrane transport AnnotationPropagation P GO:0008381 mechanosensitive monoatomic ion channel activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IBA
GO:0050658 RNA transport AnnotationPropagation P GO:0051033 RNA transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0051033 RNA transmembrane transporter activity IBA
GO:0051170 import into nucleus AnnotationPropagation P GO:0061608 nuclear import signal receptor activity IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0005242 inward rectifier potassium channel activity IBA
GO:0071897 DNA biosynthetic process AnnotationPropagation P GO:0003887 DNA-directed DNA polymerase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0042776 proton motive force-driven mitochondrial ATP synthesis IBA
GO:0006259 DNA metabolic process AnnotationPropagation P GO:0017108 5'-flap endonuclease activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0001604 urotensin II receptor activity IBA
GO:0006412 translation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0006417 regulation of translation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA