GORULE violations assigned by DisProt
Contents
gorule-0000006
IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC
gorule-0000008
No annotations should be made to uninformative high level terms
gorule-0000013
Taxon-appropriate annotation check
gorule-0000020
Automatic repair of annotations to merged or obsoleted terms
gorule-0000046
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.
gorule-0000061
Allowed gene product to term relations (gp2term)
MESSAGES
gorule-0000006
IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC
messages
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`MGI MGI:97769 Prnp enables GO:0140677 MGI:MGI:6116610|PMID:28945221 IEP F prion protein CD230|Prn-i|Prn-p|PrP|PrPC|PrPSc|Sinc protein_coding_gene taxon:10090 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P01106 MYC enables GO:0140537 PMID:8755740 IEP F Myc proto-oncogene protein MYC|BHLHE39 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P18564 ITGB6 enables GO:0140677 PMID:11821050 IEP F Integrin beta-6 ITGB6 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P40337 VHL enables GO:0003714 PMID:11641274 IEP F von Hippel-Lindau disease tumor suppressor VHL protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P46379 BAG6 enables GO:0140677 PMID:25713138 IEP F Large proline-rich protein BAG6 BAG6|BAT3|G3 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0008143 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0008266 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0034046 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q16236 NFE2L2 enables GO:0031625 PMID:16888629 IEP F Nuclear factor erythroid 2-related factor 2 NFE2L2|NRF2 protein taxon:9606 20220228 DisProt has_input(UniProtKB:Q14145)
`
- ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P06836 GAP43 enables GO:0008289 PMID:1826685 IEP F Neuromodulin GAP43 protein taxon:9913 20220228 DisProt
`
gorule-0000008
No annotations should be made to uninformative high level terms
messages
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:894679 Bach2 enables GO:0043167 MGI:MGI:7310017|PMID:25444856 EXP F BTB and CNC homology, basic leucine zipper transcription factor 2 E030004N02Rik protein_coding_gene taxon:10090 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1929258 Kcnip3 enables GO:0043167 MGI:MGI:5882899|PMID:15746104 EXP F Kv channel interacting protein 3, calsenilin 4933407H12Rik|Csen|DREAM|KChIP3|R74849 protein_coding_gene taxon:10090 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2182368 Sgk3 involved_in GO:0051179 MGI:MGI:3047534|PMID:15126499 EXP P serum/glucocorticoid regulated kinase 3 2510015P22Rik|A330005P07Rik|Cisk|cytokine-independent survival kinase|fy protein_coding_gene taxon:10090 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`ZFIN ZDB-GENE-031112-4 stm enables GO:0043167 PMID:26445027|ZFIN:ZDB-PUB-151008-2 IDA F starmaker cb885|id:ibd5112|sb:cb148|sb:cb568|sb:cb584 protein_coding_gene taxon:7955 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P0AG86 secB involved_in GO:0051179 PMID:10544036 IDA P Protein-export protein SecB secB|JW3584|b3609 protein taxon:83333 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB O14958 CASQ2 enables GO:0043167 PMID:21416293 IDA F Calsequestrin-2 CASQ2 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB O43791 SPOP involved_in GO:0051179 PMID:31624231 IDA P Speckle-type POZ protein SPOP protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P04083 ANXA1 involved_in GO:0051179 PMID:8756690 EXP P Annexin A1 ANXA1|ANX1|LPC1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P04271 S100B enables GO:0043167 PMID:18384084 EXP F Protein S100-B S100B protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P04554 PRM2 enables GO:0043167 PMID:2243113 EXP F Protamine-2 PRM2 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P06454 PTMA enables GO:0043167 PMID:34439840 EXP F Prothymosin alpha PTMA|TMSA protein taxon:9606 20220228 DisProt has_input(ChEBI:3312)
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P08631 HCK involved_in GO:0051179 PMID:31877324 EXP P Tyrosine-protein kinase HCK HCK protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P10451 SPP1 enables GO:0043167 PMID:24928493 IPI ChEBI:29108 F Osteopontin SPP1|BNSP|OPN|PSEC0156 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P10451 SPP1 enables GO:0043167 PMID:33914399 EXP F Osteopontin SPP1|BNSP|OPN|PSEC0156 protein taxon:9606 20220228 DisProt has_input(ChEBI:29108)
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P15941 MUC1 involved_in GO:0051179 PMID:26267657 IDA P Mucin-1 MUC1|PUM protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P19634 SLC9A1 enables GO:0043167 PMID:34439840 EXP F Sodium/hydrogen exchanger 1 SLC9A1|APNH1|NHE1 protein taxon:9606 20220228 DisProt has_input(ChEBI:3312)
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P19793 RXRA enables GO:0043167 PMID:9698548 EXP F Retinoic acid receptor RXR-alpha RXRA|NR2B1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P20340 RAB6A involved_in GO:0051179 PMID:18243103 EXP P Ras-related protein Rab-6A RAB6A|RAB6 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P37840 SNCA involved_in GO:0051179 PMID:11286556 EXP P Alpha-synuclein SNCA|NACP|PARK1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P38398 BRCA1 involved_in GO:0051179 PMID:9008167 IDA P Breast cancer type 1 susceptibility protein BRCA1|RNF53 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P46527 CDKN1B involved_in GO:0051179 PMID:12529437 IDA P Cyclin-dependent kinase inhibitor 1B CDKN1B|KIP1|p27 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P46527 CDKN1B involved_in GO:0051179 PMID:29410088 IMP P Cyclin-dependent kinase inhibitor 1B CDKN1B|KIP1|p27 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P53816 PLAAT3 involved_in GO:0051179 PMID:22605381 EXP P Phospholipase A and acyltransferase 3 PLAAT3|HRASLS3|HREV107|PLA2G16 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P63000 RAC1 involved_in GO:0051179 PMID:12874273 IDA P Ras-related C3 botulinum toxin substrate 1 RAC1|TC25|MIG5 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P80303 NUCB2 enables GO:0043167 PMID:32184136 EXP F Nucleobindin-2 NUCB2|NEFA protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13153 PAK1 involved_in GO:0051179 PMID:31391252 IMP P Serine/threonine-protein kinase PAK 1 PAK1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13177 PAK2 involved_in GO:0051179 PMID:31391252 IMP P Serine/threonine-protein kinase PAK 2 PAK2 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13316 DMP1 enables GO:0043167 PMID:32190922 EXP F Dentin matrix acidic phosphoprotein 1 DMP1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q14061 COX17 enables GO:0043167 PMID:18093982 EXP F Cytochrome c oxidase copper chaperone COX17 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q15582 TGFBI involved_in GO:0051179 PMID:22640878 IMP P Transforming growth factor-beta-induced protein ig-h3 TGFBI|BIGH3 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q15582 TGFBI involved_in GO:0051179 PMID:25853243 IEP P Transforming growth factor-beta-induced protein ig-h3 TGFBI|BIGH3 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q16630 CPSF6 involved_in GO:0051179 PMID:30916345 IDA P Cleavage and polyadenylation specificity factor subunit 6 CPSF6|CFIM68 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q58F21 BRDT involved_in GO:0051179 PMID:22971749 IDA P Bromodomain testis-specific protein BRDT protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q58F21 BRDT involved_in GO:0051179 PMID:22971749 IMP P Bromodomain testis-specific protein BRDT protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q7RTP6 MICAL3 involved_in GO:0051179 PMID:27528609 EXP P [F-actin]-monooxygenase MICAL3 MICAL3|KIAA0819|KIAA1364 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q8IYB3 SRRM1 involved_in GO:0051179 PMID:12624182 IDA P Serine/arginine repetitive matrix protein 1 SRRM1|SRM160 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q8WVM7 STAG1 involved_in GO:0051179 PMID:22715410 IDA P Cohesin subunit SA-1 STAG1|SA1|SCC3 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q8WVM7 STAG1 involved_in GO:0051179 PMID:22715410 IMP P Cohesin subunit SA-1 STAG1|SA1|SCC3 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q969R2 OSBP2 involved_in GO:0051179 PMID:30905771 IMP P Oxysterol-binding protein 2 OSBP2|KIAA1664|ORP4|OSBPL4 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q96H20 SNF8 involved_in GO:0051179 PMID:18539118 IDA P Vacuolar-sorting protein SNF8 SNF8|EAP30 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9BQB4 SOST involved_in GO:0051179 PMID:19208630 IEP P Sclerostin SOST|UNQ2976/PRO7455/PRO7476 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9GZU1 MCOLN1 involved_in GO:0051179 PMID:16497227 IDA P Mucolipin-1 MCOLN1|ML4|TRPML1|MSTP080 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9GZZ9 UBA5 involved_in GO:0051179 PMID:30990354 IDA P Ubiquitin-like modifier-activating enzyme 5 UBA5|UBE1DC1 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9NWW9 PLAAT2 involved_in GO:0051179 PMID:22605381 EXP P Phospholipase A and acyltransferase 2 PLAAT2|HRASLS2 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P02666 CSN2 enables GO:0043167 PMID:24918971 EXP F Beta-casein CSN2 protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P02666 CSN2 enables GO:0043167 PMID:7305393 EXP F Beta-casein CSN2 protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P04972 PDE6G enables GO:0043167 PMID:12643535 EXP F Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G|PDEG protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P04972 PDE6G enables GO:0043167 PMID:12643535 IDA F Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G|PDEG protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P06836 GAP43 involved_in GO:0051179 PMID:1826685 IEP P Neuromodulin GAP43 protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P63315 TNNC1 enables GO:0043167 PMID:2933134 EXP F Troponin C, slow skeletal and cardiac muscles TNNC1|TNNC protein taxon:9913 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB F1NGB1 NUCB2 enables GO:0043167 PMID:32184136 EXP F EF-hand domain-containing protein NUCB2 protein taxon:9031 20220228 DisProt UniProtKB:F1NGB1
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P60484 PTEN involved_in GO:0051179 PMID:23744781 IDA P Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN|MMAC1|TEP1 protein taxon:9606 20220228 DisProt UniProtKB:P60484-2
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9BZZ5 API5 involved_in GO:0051179 PMID:22334682 EXP P Apoptosis inhibitor 5 API5|MIG8 protein taxon:9606 20220228 DisProt UniProtKB:Q9BZZ5-2
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9Y237 PIN4 involved_in GO:0051179 PMID:17875217 IDA P Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 PIN4 protein taxon:9606 20220228 DisProt UniProtKB:Q9Y237-2
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P15340 P15340 enables GO:0043167 PMID:2738040 EXP F Sperm histone protein taxon:9031 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P81455 BGLAP enables GO:0043167 PMID:8218200 EXP F Osteocalcin BGLAP protein taxon:9615 20220228 DisProt has_input(ChEBI:29108)
`
gorule-0000013
Taxon-appropriate annotation check
messages
- WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB Q14457 BECN1 involved_in GO:0039521 PMID:18797192 IDA P Beclin-1 BECN1|GT197 protein taxon:9606 20220228 DisProt
`
gorule-0000020
Automatic repair of annotations to merged or obsoleted terms
messages
- ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P06748 NPM1 enables GO:0043621 PMID:24106084 IPI UniProtKB:P06748 F Nucleophosmin NPM1|NPM protein taxon:9606 20220228 DisProt
`
gorule-0000046
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.
messages
- WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P80723 BASP1 involved_in GO:0051260 PMID:32750402 IDA P Brain acid soluble protein 1 BASP1|NAP22 protein taxon:9606 20220228 DisProt
`
gorule-0000061
Allowed gene product to term relations (gp2term)
messages
- WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q16236 NFE2L2 is_active_in GO:0016592 PMID:32727915 EXP C Nuclear factor erythroid 2-related factor 2 NFE2L2|NRF2 protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q92574 TSC1 is_active_in GO:0033596 PMID:26893383 EXP C Hamartin TSC1|KIAA0243|TSC protein taxon:9606 20220228 DisProt
`
- WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB O43561 LAT is_active_in GO:0036398 PMID:33080222 IDA C Linker for activation of T-cells family member 1 LAT protein taxon:9606 20220228 DisProt UniProtKB:O43561-2
`