GORULE violations assigned by ARUK-UCL
Contents
gorule-0000008
GORULE:0000008: No annotations should be made to uninformatively high level terms
gorule-0000020
Violates GORULE:0000020
gorule-0000046
GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms
gorule-0000061
GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050
MESSAGES
gorule-0000008
GORULE:0000008: No annotations should be made to uninformatively high level terms
messages
- MGI MGI:99606 Abca2 acts_upstream_of GO:1905598 MGI:MGI:5306885|PMID:21810484 IDA P ATP-binding cassette, sub-family A member 2 Abc2|D2H0S1474E protein_coding_gene taxon:10090 20190726 ARUK-UCL occurs_in(CL:0000540)
- MGI MGI:87904 Actb involved_in GO:0032091 MGI:MGI:3829808|PMID:19118186 IDA P actin, beta Actx|A-X actin-like protein|beta-actin|E430023M04Rik protein_coding_gene taxon:10090 20171103 ARUK-UCL has_input(UniProtKB:P61809),has_input(UniProtKB:P49615)
- MGI MGI:87904 Actb involved_in GO:1904030 MGI:MGI:3829808|PMID:19118186 IC GO:0032091 P actin, beta Actx|A-X actin-like protein|beta-actin|E430023M04Rik protein_coding_gene taxon:10090 20171103 ARUK-UCL has_input(UniProtKB:P49615)
- MGI MGI:2385110 Aph1a involved_in GO:0010950 MGI:MGI:6478051|PMID:12522139 IMP P aph1 homolog A, gamma secretase subunit 6530402N02Rik protein_coding_gene taxon:10090 20201110 ARUK-UCL has_input(UniProtKB:P49769)
- MGI MGI:88108 Atp1b1 involved_in GO:1903408 MGI:MGI:4359299|PMID:19683723 IMP P ATPase, Na+/K+ transporting, beta 1 polypeptide Atpb|Atpb-1|sodium/potassium ATPase beta subunit protein_coding_gene taxon:10090 20200717 ARUK-UCL occurs_in(EMAPA:16105)
- MGI MGI:108092 Bin1 involved_in GO:1902960 MGI:MGI:5811968|PMID:27179792 IMP P bridging integrator 1 Amphiphysin 2|Amphl protein_coding_gene taxon:10090 20190717 ARUK-UCL occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000119),has_input(UniProtKB:P56818)|occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000118),has_input(UniProtKB:P56818)|occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000116),has_input(UniProtKB:P56818)
- MGI MGI:88232 C5ar1 involved_in GO:1902947 MGI:MGI:4354701|PMID:19561098 IGI UniProtKB:P05067 P complement component 5a receptor 1 C5aR|C5r1|Cd88|D7Msu1 protein_coding_gene taxon:10090 20190104 ARUK-UCL occurs_in(EMAPA:35405)
- MGI MGI:103250 Calm2 involved_in GO:1901020 MGI:MGI:6716978|PMID:33199372 IDA P calmodulin 2 1500001E21Rik protein_coding_gene taxon:10090 20210421 ARUK-UCL has_input(UniProtKB:Q8CGQ8),part_of(GO:1905913),occurs_in(EMAPA:16894)
- MGI MGI:101765 Cdk5 involved_in GO:0018105 MGI:MGI:6094501|PMID:24607229 IMP P cyclin dependent kinase 5 Crk6 protein_coding_gene taxon:10090 20171030 ARUK-UCL has_input(UniProtKB:Q01097),occurs_in(EMAPA:35405),regulates(GO:0072659)
- MGI MGI:101765 Cdk5 involved_in GO:0018107 MGI:MGI:6094501|PMID:24607229 IMP P cyclin dependent kinase 5 Crk6 protein_coding_gene taxon:10090 20171030 ARUK-UCL has_input(UniProtKB:Q60829),occurs_in(EMAPA:35405)
- MGI MGI:99779 Chrna7 involved_in GO:1905920 MGI:MGI:4437154|PMID:20164328 IGI UniProtKB:P05067 P cholinergic receptor, nicotinic, alpha polypeptide 7 Acra7|alpha7|alpha7-nAChR|alpha7 nicotinic receptor protein_coding_gene taxon:10090 20170208 ARUK-UCL has_input(UniProtKB:P12023),happens_during(UBERON:0018241),occurs_in(EMAPA:35405),has_input(UniProtKB:Q03059)|has_input(UniProtKB:P12023),happens_during(UBERON:0018241),occurs_in(EMAPA:35164),has_input(UniProtKB:Q03059)
- MGI MGI:1861431 Clec7a acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P C-type lectin domain family 7, member a beta-glucan receptor|beta-GR|BGR|Clecsf12|dectin-1 pseudogene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:Q60591),part_of(GO:0001878)
- MGI MGI:1861431 Clec7a acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P C-type lectin domain family 7, member a beta-glucan receptor|beta-GR|BGR|Clecsf12|dectin-1 pseudogene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:P05627),part_of(GO:0001878)
- MGI MGI:1861431 Clec7a acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P C-type lectin domain family 7, member a beta-glucan receptor|beta-GR|BGR|Clecsf12|dectin-1 pseudogene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:P97305),part_of(GO:0001878)
- MGI MGI:1861431 Clec7a involved_in GO:0051092 MGI:MGI:3844414|PMID:19136564 IDA P C-type lectin domain family 7, member a beta-glucan receptor|beta-GR|BGR|Clecsf12|dectin-1 pseudogene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:0001878)
- MGI MGI:1298217 Cst7 involved_in GO:0010466 MGI:MGI:6294189|PMID:18256700 IDA P cystatin F (leukocystatin) CMAP|cystatin-like metastasis-associated protein|Leukocystatin protein_coding_gene taxon:10090 20190228 ARUK-UCL has_input(UniProtKB:P97821)
- MGI MGI:2447658 Disc1 involved_in GO:0032091 MGI:MGI:5908529|PMID:26078884 IDA P disrupted in schizophrenia 1 protein_coding_gene taxon:10090 20170814 ARUK-UCL has_input(UniProtKB:P97924),has_input(UniProtKB:Q99K10)
- MGI MGI:1329040 Dkk1 involved_in GO:1902949 MGI:MGI:5897547|PMID:23164821 IDA P dickkopf WNT signaling pathway inhibitor 1 mdkk-1 protein_coding_gene taxon:10090 20170428 ARUK-UCL occurs_in(EMAPA:35405),happens_during(UBERON:0007222),causally_upstream_of(GO:0007611)
- MGI MGI:1330299 Dyrk1a involved_in GO:0038083 MGI:MGI:6107410|PMID:24327345 IDA P dual-specificity tyrosine phosphorylation regulated kinase 1a 2310043O08Rik|D16Ertd272e|D16Ertd493e|Dyrk|Mnbh protein_coding_gene taxon:10090 20171205 ARUK-UCL occurs_in(GO:0005829)
- MGI MGI:98277 Epha4 involved_in GO:0061098 MGI:MGI:5588508|PMID:24658113 IGI ComplexPortal:CPX-1134 P Eph receptor A4 2900005C20Rik|Cek8|Hek8|rb|Sek|Sek1|Tyro1 protein_coding_gene taxon:10090 20170627 ARUK-UCL occurs_in(CL:0002608),has_input(UniProtKB:P00520)
- MGI MGI:99611 Ephb2 acts_upstream_of GO:0006469 MGI:MGI:5905277|PMID:11585923 IDA P Eph receptor B2 Cek5|Drt|Erk|eteck|Hek5|Nuk|Prkm5|Qek5|Sek3|Tyro5 protein_coding_gene taxon:10090 20210421 ARUK-UCL
- MGI MGI:99611 Ephb2 involved_in GO:0018108 MGI:MGI:4867584|PMID:21113149 IMP P Eph receptor B2 Cek5|Drt|Erk|eteck|Hek5|Nuk|Prkm5|Qek5|Sek3|Tyro5 protein_coding_gene taxon:10090 20170620 ARUK-UCL has_input(UniProtKB:P35438)
- MGI MGI:99611 Ephb2 involved_in GO:1904782 MGI:MGI:4867584|PMID:21113149 IMP P Eph receptor B2 Cek5|Drt|Erk|eteck|Hek5|Nuk|Prkm5|Qek5|Sek3|Tyro5 protein_coding_gene taxon:10090 20170620 ARUK-UCL causally_upstream_of(GO:1900272),occurs_in(CL:2000089)
- MGI MGI:99611 Ephb2 involved_in GO:1904783 MGI:MGI:4867584|PMID:21113149 IMP P Eph receptor B2 Cek5|Drt|Erk|eteck|Hek5|Nuk|Prkm5|Qek5|Sek3|Tyro5 protein_coding_gene taxon:10090 20170620 ARUK-UCL causally_upstream_of(GO:1900273),occurs_in(CL:2000089)
- MGI MGI:95499 Fcgr2b involved_in GO:0051091 MGI:MGI:5514474|PMID:23921129 IMP P Fc receptor, IgG, low affinity IIb CD32|F630109E10Rik|FcgammaRIIB|Fc gamma RIIB|Fcgr2|Fcgr2a|FcgRII|Fc[g]RII|Fcr-2|Fcr-3|Ly-17|LyM-1|Ly-m20 protein_coding_gene taxon:10090 20230517 ARUK-UCL occurs_in(CL:0010012),part_of(GO:1904646)
- MGI MGI:95602 Fyn involved_in GO:0018108 MGI:MGI:5811735|PMID:27525436 IMP P Fyn proto-oncogene Src Kinase p59 protein_coding_gene taxon:10090 20180509 ARUK-UCL has_input(UniProtKB:Q9JHI8),occurs_in(EMAPA:16105),negatively_regulates(GO:1903409)
- MGI MGI:1351342 Grm5 involved_in GO:0061098 MGI:MGI:5515653|PMID:24012003 IGI ComplexPortal:CPX-1134 P glutamate receptor, metabotropic 5 6430542K11Rik|Glu5R|Gprc1e|mGluR5 protein_coding_gene taxon:10090 20170628 ARUK-UCL has_input(UniProtKB:P39688),occurs_in(CL:0010012)
- MGI MGI:2152453 Gsk3a involved_in GO:0018105 MGI:MGI:6094357|PMID:16537926 IGI UniProtKB:Q9WV60 P glycogen synthase kinase 3 alpha 2700086H06Rik protein_coding_gene taxon:10090 20171018 ARUK-UCL has_input(UniProtKB:Q8VI36)
- MGI MGI:1861437 Gsk3b involved_in GO:0018105 MGI:MGI:6094357|PMID:16537926 IGI UniProtKB:Q2NL51 P glycogen synthase kinase 3 beta 7330414F15Rik|8430431H08Rik|GSK3|GSK-3|GSK-3beta protein_coding_gene taxon:10090 20171018 ARUK-UCL has_input(UniProtKB:Q8VI36)
- MGI MGI:1333752 Hdac6 involved_in GO:0034983 MGI:MGI:6114855|PMID:23962722 IMP P histone deacetylase 6 mHDA2|Sfc6 protein_coding_gene taxon:10090 20180126 ARUK-UCL has_input(UniProtKB:P10637)
- MGI MGI:104853 Hes1 involved_in GO:0043433 MGI:MGI:1859234|PMID:10851137 IDA P hes family bHLH transcription factor 1 bHLHb39|Hry protein_coding_gene taxon:10090 20200505 ARUK-UCL
- MGI MGI:1859852 Hes6 involved_in GO:0043433 MGI:MGI:1859234|PMID:10851137 IDA P hairy and enhancer of split 6 bHLHb41 protein_coding_gene taxon:10090 20200505 ARUK-UCL has_input(UniProtKB:P35428)
- MGI MGI:96247 Hsp90ab1 involved_in GO:1904031 MGI:MGI:6148636|PMID:17517623 IMP P heat shock protein 90 alpha (cytosolic), class B member 1 C81438|Hsp84|Hsp84-1|Hsp90|Hspcb protein_coding_gene taxon:10090 20180226 ARUK-UCL occurs_in(EMAPA:16894)
- MGI MGI:96067 Htt involved_in GO:2000479 MGI:MGI:5293262|PMID:21768291 IMP P huntingtin C430023I11Rik|HD|Hdh|htt|huntingtin|IT15 protein_coding_gene taxon:10090 20180515 ARUK-UCL has_input(UniProtKB:Q5EG47),occurs_in(EMAPA:17549)
- MGI MGI:107656 Ifng involved_in GO:2000273 MGI:MGI:5776417|PMID:26227742 IGI UniProtKB:P05067,UniProtKB:P49768 P interferon gamma Ifg|IFN-gamma protein_coding_gene taxon:10090 20201016 ARUK-UCL has_input(UniProtKB:P27512),occurs_in(CL:0000129)
- MGI MGI:96607 Itgam involved_in GO:2000363 MGI:MGI:3814938|PMID:18981141 IMP P integrin alpha M Cd11b|CD11b/CD18|CD11B (p170)|complement component receptor 3 alpha|complement receptor type 3|CR3|F730045J24Rik|Ly-40|Mac-1|Mac-1a|Mac-1 alpha protein_coding_gene taxon:10090 20210429 ARUK-UCL occurs_in(EMAPA:16974),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)
- MGI MGI:96610 Itgb1 acts_upstream_of_or_within GO:1901979 MGI:MGI:5629870|PMID:25716834 IMP P integrin beta 1 (fibronectin receptor beta) 4633401G24Rik|beta1 integrin|CD29|Fnrb|Gm9863 protein_coding_gene taxon:10090 20200116 ARUK-UCL occurs_in(EMAPA:35184),occurs_in(CL:0000127)
- MGI MGI:96629 Jak2 involved_in GO:2000273 MGI:MGI:5776417|PMID:26227742 IGI UniProtKB:P01580 P Janus kinase 2 C81284 protein_coding_gene taxon:10090 20201016 ARUK-UCL has_input(UniProtKB:P27512),occurs_in(CL:0000129)
- MGI MGI:1346881 Map3k12 involved_in GO:0018105 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 12 DLK|MUK|Zpk protein_coding_gene taxon:10090 20180716 ARUK-UCL has_input(UniProtKB:P47809),occurs_in(CL:0000540)
- MGI MGI:1346881 Map3k12 involved_in GO:0043507 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 12 DLK|MUK|Zpk protein_coding_gene taxon:10090 20210421 ARUK-UCL has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)
- MGI MGI:1346881 Map3k12 involved_in GO:0045860 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 12 DLK|MUK|Zpk protein_coding_gene taxon:10090 20210421 ARUK-UCL has_input(UniProtKB:P47809),occurs_in(CL:0000540)
- MGI MGI:2444243 Map3k13 involved_in GO:0018105 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 13 C130026N12Rik protein_coding_gene taxon:10090 20180716 ARUK-UCL has_input(UniProtKB:P45985),occurs_in(CL:0000540)
- MGI MGI:2444243 Map3k13 involved_in GO:0043507 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 13 C130026N12Rik protein_coding_gene taxon:10090 20210421 ARUK-UCL has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)
- MGI MGI:2444243 Map3k13 involved_in GO:0045860 MGI:MGI:5810221|PMID:27511108 IMP P mitogen-activated protein kinase kinase kinase 13 C130026N12Rik protein_coding_gene taxon:10090 20210421 ARUK-UCL has_input(UniProtKB:P47809),occurs_in(CL:0000540)
- MGI MGI:1349394 Map4k4 involved_in GO:0043547 MGI:MGI:6189265|PMID:25490267 IMP P mitogen-activated protein kinase kinase kinase kinase 4 9430080K19Rik|Nik protein_coding_gene taxon:10090 20180627 ARUK-UCL occurs_in(CL:0000312),has_input(UniProtKB:P62331)
- MGI MGI:106271 Mapre2 involved_in GO:0043547 MGI:MGI:6189265|PMID:25490267 IMP P microtubule-associated protein, RP/EB family, member 2 C820009F03Rik|D18Abb1e|EB2|RP1 protein_coding_gene taxon:10090 20180627 ARUK-UCL occurs_in(CL:0000312),has_input(UniProtKB:P62331)
- MGI MGI:1341865 Mark3 involved_in GO:0018105 MGI:MGI:6154657|PMID:9543386 ISS UniProtKB:P27448 P MAP/microtubule affinity regulating kinase 3 1600015G02Rik|A430080F22Rik|C-TAK1|ETK-1 protein_coding_gene taxon:10090 20180328 ARUK-UCL has_input(UniProtKB:P48967),positively_regulates(GO:0005515)
- MGI MGI:1341865 Mark3 involved_in GO:0032092 MGI:MGI:6154657|PMID:9543386 ISS UniProtKB:P27448 P MAP/microtubule affinity regulating kinase 3 1600015G02Rik|A430080F22Rik|C-TAK1|ETK-1 protein_coding_gene taxon:10090 20180328 ARUK-UCL has_input(UniProtKB:P48967),has_input(UniProtKB:P63101)
- MGI MGI:1341865 Mark3 involved_in GO:0036289 MGI:MGI:6154657|PMID:9543386 ISS UniProtKB:P27448 P MAP/microtubule affinity regulating kinase 3 1600015G02Rik|A430080F22Rik|C-TAK1|ETK-1 protein_coding_gene taxon:10090 20180328 ARUK-UCL has_input(UniProtKB:Q03141)
- MGI MGI:97321 Ngf involved_in GO:0043388 MGI:MGI:6115179|PMID:10362258 IMP P nerve growth factor Ngfb protein_coding_gene taxon:10090 20180124 ARUK-UCL has_input(UniProtKB:B2RWS6),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:O89090),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:O70494),has_input(UniProtKB:P38936),has_input(CHEBI:4705)
- MGI MGI:1354184 Nox4 involved_in GO:0061098 MGI:MGI:5811735|PMID:27525436 IDA P NADPH oxidase 4 protein_coding_gene taxon:10090 20230605 ARUK-UCL occurs_in(CL:0000746),has_input(UniProtKB:P39688),part_of(GO:0006979)
- MGI MGI:97616 Plcg2 acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P phospholipase C, gamma 2 Plcg-2|PLCgamma2 protein_coding_gene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P97305)
- MGI MGI:97616 Plcg2 acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P phospholipase C, gamma 2 Plcg-2|PLCgamma2 protein_coding_gene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P05627)
- MGI MGI:97616 Plcg2 acts_upstream_of_or_within GO:0051091 MGI:MGI:3844414|PMID:19136564 IMP P phospholipase C, gamma 2 Plcg-2|PLCgamma2 protein_coding_gene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q60591)
- MGI MGI:97616 Plcg2 involved_in GO:0051092 MGI:MGI:3844414|PMID:19136564 IMP P phospholipase C, gamma 2 Plcg-2|PLCgamma2 protein_coding_gene taxon:10090 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858)
- MGI MGI:99879 Prkd1 acts_upstream_of GO:0018107 MGI:MGI:6221361|PMID:27782176 IMP P protein kinase D1 Pkcm|PKD1|Prkcm protein_coding_gene taxon:10090 20200119 ARUK-UCL has_input(UniProtKB:Q924N4)
- MGI MGI:97769 Prnp involved_in GO:0032147 MGI:MGI:5882868|PMID:23386614 IGI ComplexPortal:CPX-1134 P prion protein CD230|Prn-i|Prn-p|PrP|PrPC|PrPSc|Sinc protein_coding_gene taxon:10090 20210428 ARUK-UCL has_input(UniProtKB:P06241),occurs_in(GO:0045121)
- MGI MGI:1913590 Psenen involved_in GO:0010950 MGI:MGI:6478051|PMID:12522139 IMP P presenilin enhancer gamma secretase subunit 1700023M09Rik|Pen2 protein_coding_gene taxon:10090 20201110 ARUK-UCL has_input(UniProtKB:P49769)
- MGI MGI:97810 Ptprc involved_in GO:0061099 MGI:MGI:3530407|PMID:15661907 IGI UniProtKB:P06240 P protein tyrosine phosphatase receptor type C B220|CD45|Ly-5|Lyt-4|T200 protein_coding_gene taxon:10090 20180723 ARUK-UCL occurs_in(CL:0000084),occurs_in(GO:0045121),has_input(UniProtKB:O54957)
- MGI MGI:97810 Ptprc involved_in GO:1903615 MGI:MGI:3530407|PMID:15661907 IGI UniProtKB:P05480|UniProtKB:P06240 P protein tyrosine phosphatase receptor type C B220|CD45|Ly-5|Lyt-4|T200 protein_coding_gene taxon:10090 20180723 ARUK-UCL occurs_in(CL:0000084)
- MGI MGI:107926 Rock2 involved_in GO:0018105 MGI:MGI:6114922|PMID:24305806 IMP P Rho-associated coiled-coil containing protein kinase 2 B230113H15Rik|Rho-kinase|Rock2m|Rock-II|ROKalpha protein_coding_gene taxon:10090 20180111 ARUK-UCL has_input(UniProtKB:P51667),occurs_in(CL:0010012)
- MGI MGI:107926 Rock2 involved_in GO:0018107 MGI:MGI:6271078|PMID:29353861 IMP P Rho-associated coiled-coil containing protein kinase 2 B230113H15Rik|Rho-kinase|Rock2m|Rock-II|ROKalpha protein_coding_gene taxon:10090 20181204 ARUK-UCL causally_upstream_of(GO:0050115),occurs_in(CL:2000044)|causally_upstream_of(GO:0050115),occurs_in(CL:0010008)
- MGI MGI:107926 Rock2 involved_in GO:0018107 MGI:MGI:6271078|PMID:29353861 IMP P Rho-associated coiled-coil containing protein kinase 2 B230113H15Rik|Rho-kinase|Rock2m|Rock-II|ROKalpha protein_coding_gene taxon:10090 20181204 ARUK-UCL has_input(UniProtKB:P10126),occurs_in(CL:2000044),part_of(GO:0061157)
- MGI MGI:107926 Rock2 involved_in GO:1902961 MGI:MGI:6114922|PMID:24305806 IMP P Rho-associated coiled-coil containing protein kinase 2 B230113H15Rik|Rho-kinase|Rock2m|Rock-II|ROKalpha protein_coding_gene taxon:10090 20180111 ARUK-UCL occurs_in(EMAPA:35279),has_input(UniProtKB:P56818)|occurs_in(EMAPA:35667),has_input(UniProtKB:P56818)
- MGI MGI:2447362 Slc24a4 acts_upstream_of GO:0010469 MGI:MGI:6716959|PMID:25096581 IMP UniProtKB:P56450 P solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 A930002M03Rik|NCKX4 protein_coding_gene taxon:10090 20210601 ARUK-UCL has_input(UniProtKB:P56450),part_of(GO:0008277),occurs_in(EMAPA:17536),occurs_in(CL:0000540)
- MGI MGI:1858226 Slc5a3 acts_upstream_of_or_within GO:0043085 MGI:MGI:6414721|PMID:28128227 IMP P solute carrier family 5 (inositol transporters), member 3 Smit1 protein_coding_gene taxon:10090 20200329 ARUK-UCL occurs_in(CL:0000746),has_input(UniProtKB:Q61093)
- MGI MGI:95760 Slc6a9 acts_upstream_of GO:1904782 MGI:MGI:3044468|PMID:15159536 IMP P solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Glyt1|Glyt-1 protein_coding_gene taxon:10090 20200612 ARUK-UCL occurs_in(CL:1001571)
- MGI MGI:107956 Slc8a1 acts_upstream_of_or_within GO:0071901 MGI:MGI:6282180|PMID:29274751 IMP P solute carrier family 8 (sodium/calcium exchanger), member 1 D930008O12Rik|Ncx1 protein_coding_gene taxon:10090 20191210 ARUK-UCL occurs_in(EMAPA:35405),has_input(UniProtKB:Q9UQM7)
- MGI MGI:107996 Slc8a2 acts_upstream_of_or_within GO:0071902 MGI:MGI:6282180|PMID:29274751 IMP P solute carrier family 8 (sodium/calcium exchanger), member 2 Ncx2 protein_coding_gene taxon:10090 20191210 ARUK-UCL occurs_in(EMAPA:35405),has_input(UniProtKB:Q9UQM7)
- MGI MGI:107976 Slc8a3 acts_upstream_of_or_within GO:0071901 MGI:MGI:6282180|PMID:29274751 IMP P solute carrier family 8 (sodium/calcium exchanger), member 3 Ncx3 protein_coding_gene taxon:10090 20191210 ARUK-UCL occurs_in(EMAPA:35405),has_input(UniProtKB:Q9UQM7)
- MGI MGI:98282 Spi1 involved_in GO:0051090 MGI:MGI:6284428|PMID:29924977 IMP P spleen focus forming virus (SFFV) proviral integration oncogene Dis-1|PU.1|Sfpi1|Sfpi-1|Spi-1|Tcfpu1|Tfpu.1 protein_coding_gene taxon:10090 20201202 ARUK-UCL happens_during(GO:0002572),has_input(UniProtKB:Q60611)|happens_during(GO:0002572),has_input(UniProtKB:Q03347)
- MGI MGI:1858416 Stk39 involved_in GO:0018107 MGI:MGI:6221361|PMID:27782176 IMP P serine/threonine kinase 39 DCHT|RF005|Rnl5|SPAK protein_coding_gene taxon:10090 20200119 ARUK-UCL has_input(UniProtKB:Q924N4)
- MGI MGI:1913150 Trem2 involved_in GO:1901980 MGI:MGI:6150565|PMID:29518356 IMP P triggering receptor expressed on myeloid cells 2 Trem2a|Trem2b|Trem2c protein_coding_gene taxon:10090 20181212 ARUK-UCL occurs_in(CL:0000129)
- MGI MGI:2147036 Ttbk1 involved_in GO:0018105 MGI:MGI:6102319|PMID:16923168 ISS UniProtKB:Q5TCY1 P tau tubulin kinase 1 C330008L01Rik protein_coding_gene taxon:10090 20190619 ARUK-UCL has_input(UniProtKB:P10637),positively_regulates(GO:0051258)
- MGI MGI:2147036 Ttbk1 involved_in GO:0018107 MGI:MGI:6102319|PMID:16923168 ISS UniProtKB:Q5TCY1 P tau tubulin kinase 1 C330008L01Rik protein_coding_gene taxon:10090 20190619 ARUK-UCL has_input(UniProtKB:P10637),positively_regulates(GO:0051258)
- MGI MGI:2147036 Ttbk1 involved_in GO:0018108 MGI:MGI:6102319|PMID:16923168 ISS UniProtKB:Q5TCY1 P tau tubulin kinase 1 C330008L01Rik protein_coding_gene taxon:10090 20190619 ARUK-UCL has_input(UniProtKB:P10637)
- MGI MGI:2442092 Wnk1 acts_upstream_of GO:0018107 MGI:MGI:6221361|PMID:27782176 IMP P WNK lysine deficient protein kinase 1 6430573H23Rik|EG406236|Hsn2|Prkwnk1 protein_coding_gene taxon:10090 20200119 ARUK-UCL has_input(UniProtKB:Q924N4)
- MGI MGI:2652875 Wnk3 acts_upstream_of GO:0018107 MGI:MGI:6221361|PMID:27782176 IMP P WNK lysine deficient protein kinase 3 Prkwnk3|Wnk3|Wnk3-ps protein_coding_gene taxon:10090 20200119 ARUK-UCL has_input(UniProtKB:Q924N4),causally_upstream_of(GO:1904062)
- UniProtKB P05027 ATP1B1 involved_in GO:1903408 PMID:18052210 IGI UniProtKB:P05023 P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1 protein taxon:9823 20200717 ARUK-UCL
- UniProtKB O00206 TLR4 acts_upstream_of GO:0051092 PMID:30233718 IMP P Toll-like receptor 4 TLR4 protein taxon:9606 20201102 ARUK-UCL
- UniProtKB O00206 TLR4 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:P05067-PRO_0000000092,UniProtKB:P16671,UniProtKB:Q9Y2C9 P Toll-like receptor 4 TLR4 protein taxon:9606 20170517 ARUK-UCL
- UniProtKB O00206 TLR4 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:P16671,UniProtKB:Q9Y2C9 P Toll-like receptor 4 TLR4 protein taxon:9606 20170517 ARUK-UCL occurs_in(CL:0000235),positively_regulates(GO:0002269),part_of(GO:0071404)
- UniProtKB O00410 IPO5 involved_in GO:0045736 PMID:17491008 TAS P Importin-5 IPO5|KPNB3|RANBP5 protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:Q00535)
- UniProtKB O00499 BIN1 involved_in GO:1902960 PMID:27179792 IMP P Myc box-dependent-interacting protein 1 BIN1|AMPHL protein taxon:9606 20190717 ARUK-UCL has_output(UniProtKB:P05067-PRO_0000000093),has_input(UniProtKB:P56817)|has_output(UniProtKB:P05067-PRO_0000000092),has_input(UniProtKB:P56817)
- UniProtKB O00501 CLDN5 involved_in GO:0032092 PMID:25323998 IMP P Claudin-5 CLDN5|AWAL|TMVCF protein taxon:9606 20190702 ARUK-UCL occurs_in(CL:0002585),has_input(UniProtKB:O95832),has_input(UniProtKB:P57739)|occurs_in(CL:0002586),has_input(UniProtKB:O95832),has_input(UniProtKB:P57739)
- UniProtKB O14493 CLDN4 involved_in GO:1905050 PMID:16103090 IMP P Claudin-4 CLDN4|CPER|CPETR1|WBSCR8 protein taxon:9606 20190912 ARUK-UCL occurs_in(CL:2000064),has_input(UniProtKB:P08253)
- UniProtKB O14522 PTPRT involved_in GO:0035335 PMID:17360477 IDA P Receptor-type tyrosine-protein phosphatase T PTPRT|KIAA0283 protein taxon:9606 20180803 ARUK-UCL has_input(UniProtKB:P40763),part_of(GO:1904893)
- UniProtKB O14522 PTPRT involved_in GO:1990264 PMID:24846175 IDA P Receptor-type tyrosine-protein phosphatase T PTPRT|KIAA0283 protein taxon:9606 20180803 ARUK-UCL
- UniProtKB O15244 SLC22A2 acts_upstream_of GO:0006919 GO_REF:0000024 ISS UniProtKB:Q9R0W2 P Solute carrier family 22 member 2 SLC22A2|OCT2 protein taxon:9606 20200501 ARUK-UCL has_input(UniProtKB:P42574),occurs_in(CL:0002306)
- UniProtKB O15551 CLDN3 involved_in GO:1905050 PMID:16103090 IMP P Claudin-3 CLDN3|C7orf1|CPETR2 protein taxon:9606 20190912 ARUK-UCL occurs_in(CL:2000064),has_input(UniProtKB:P08253)
- UniProtKB O43283 MAP3K13 involved_in GO:0043507 GO_REF:0000024 ISS UniProtKB:Q1HKZ5 P Mitogen-activated protein kinase kinase kinase 13 MAP3K13|LZK protein taxon:9606 20210421 ARUK-UCL has_input(UniProtKB:P45984),occurs_in(CL:0000540)|has_input(UniProtKB:P45983),occurs_in(CL:0000540)
- UniProtKB O43283 MAP3K13 involved_in GO:0043507 GO_REF:0000024 ISS UniProtKB:Q1HKZ5 P Mitogen-activated protein kinase kinase kinase 13 MAP3K13|LZK protein taxon:9606 20210421 ARUK-UCL has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)
- UniProtKB O43504 LAMTOR5 acts_upstream_of GO:1905636 PMID:21343296 IDA P Ragulator complex protein LAMTOR5 LAMTOR5|HBXIP|XIP protein taxon:9606 20191029 ARUK-UCL has_input(UniProtKB:Q04206)
- UniProtKB O43504 LAMTOR5 acts_upstream_of_or_within GO:0051092 PMID:21343296 IGI UniProtKB:Q04206 P Ragulator complex protein LAMTOR5 LAMTOR5|HBXIP|XIP protein taxon:9606 20191029 ARUK-UCL has_input(UniProtKB:P10145)
- UniProtKB O60674 JAK2 involved_in GO:2000273 GO_REF:0000024 ISS UniProtKB:Q62120 P Tyrosine-protein kinase JAK2 JAK2 protein taxon:9606 20201016 ARUK-UCL has_input(UniProtKB:P27512),occurs_in(CL:0000129)
- UniProtKB O75116 ROCK2 involved_in GO:0018105 PMID:24305806 IMP P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20180111 ARUK-UCL has_input(UniProtKB:P56817),positively_regulates(GO:0004190)
- UniProtKB O75116 ROCK2 involved_in GO:0018105 PMID:24305806 ISS UniProtKB:P70336 P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20180111 ARUK-UCL has_input(UniProtKB:P10916),occurs_in(CL:0010012)
- UniProtKB O75116 ROCK2 involved_in GO:0018107 GO_REF:0000024 ISS UniProtKB:P70336 P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20181204 ARUK-UCL causally_upstream_of(GO:0050115),occurs_in(CL:2000044)|causally_upstream_of(GO:0050115),occurs_in(CL:0010008)
- UniProtKB O75116 ROCK2 involved_in GO:0018107 GO_REF:0000024 ISS UniProtKB:P70336 P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20181204 ARUK-UCL has_input(UniProtKB:P10126),occurs_in(CL:2000044),part_of(GO:0061157)
- UniProtKB O75116 ROCK2 involved_in GO:0018107 PMID:24305806 IMP P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20180111 ARUK-UCL has_input(UniProtKB:P05067),positively_regulates(GO:0042987),positively_regulates(GO:0034205),has_output(UniProtKB:P05067)|has_input(UniProtKB:P05067),positively_regulates(GO:0042987),positively_regulates(GO:0034205),has_output(UniProtKB:P05067-PRO_0000000092)|has_input(UniProtKB:P05067),positively_regulates(GO:0042987),has_output(UniProtKB:P05067-PRO_0000000090)
- UniProtKB O75116 ROCK2 involved_in GO:0018107 PMID:29353861 IMP P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20181204 ARUK-UCL has_input(UniProtKB:P68104),occurs_in(CL:2000044)|causally_upstream_of(GO:0050115),occurs_in(CL:2000044)
- UniProtKB O75116 ROCK2 involved_in GO:1902961 PMID:24305806 IMP P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20180111 ARUK-UCL has_input(UniProtKB:P56817)
- UniProtKB O75116 ROCK2 involved_in GO:1902961 PMID:24305806 ISS UniProtKB:P70336 P Rho-associated protein kinase 2 ROCK2|KIAA0619 protein taxon:9606 20180111 ARUK-UCL occurs_in(UBERON:0004679),has_input(UniProtKB:P56817)|occurs_in(UBERON:0016530),has_input(UniProtKB:P56817)
- UniProtKB O75955 FLOT1 involved_in GO:0051092 PMID:23319823 IMP P Flotillin-1 FLOT1 protein taxon:9606 20181203 ARUK-UCL
- UniProtKB O76096 CST7 involved_in GO:0010466 PMID:15752368 IDA P Cystatin-F CST7 protein taxon:9606 20190227 ARUK-UCL has_input(UniProtKB:P00784),has_input(UniProtKB:Q9UBX1),has_input(UniProtKB:P43235),has_input(UniProtKB:O60911),has_input(UniProtKB:P09668),has_input(UniProtKB:P25774)
- UniProtKB O76096 CST7 involved_in GO:0010466 PMID:18256700 IDA P Cystatin-F CST7 protein taxon:9606 20190227 ARUK-UCL has_input(UniProtKB:P07711),has_input(UniProtKB:P53634)
- UniProtKB O76096 CST7 involved_in GO:0010466 PMID:22365146 IDA P Cystatin-F CST7 protein taxon:9606 20190430 ARUK-UCL has_input(UniProtKB:P09668)|has_input(UniProtKB:P07711)|has_input(UniProtKB:P25774)
- UniProtKB O94907 DKK1 involved_in GO:0043507 PMID:23164821 IDA P Dickkopf-related protein 1 DKK1|UNQ492/PRO1008 protein taxon:9606 20230301 ARUK-UCL occurs_in(CL:0010012)
- UniProtKB O94907 DKK1 involved_in GO:1902949 GO_REF:0000024 ISS UniProtKB:O54908 P Dickkopf-related protein 1 DKK1|UNQ492/PRO1008 protein taxon:9606 20170428 ARUK-UCL occurs_in(UBERON:0002421),happens_during(UBERON:0007222),causally_upstream_of(GO:0007611)
- UniProtKB O95373 IPO7 involved_in GO:0045736 PMID:17491008 TAS P Importin-7 IPO7|RANBP7 protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:Q00535)
- UniProtKB O95816 BAG2 involved_in GO:0032091 PMID:16207813 IDA P BAG family molecular chaperone regulator 2 BAG2 protein taxon:9606 20180305 ARUK-UCL has_input(UniProtKB:Q9UNE7),has_input(UniProtKB:P62837),negatively_regulates(GO:0061630)
- UniProtKB O95816 BAG2 involved_in GO:1904667 PMID:16207813 IDA P BAG family molecular chaperone regulator 2 BAG2 protein taxon:9606 20180305 ARUK-UCL has_input(UniProtKB:Q9UNE7)
- UniProtKB O95819 MAP4K4 involved_in GO:0043547 PMID:25490267 ISS UniProtKB:P97820 P Mitogen-activated protein kinase kinase kinase kinase 4 MAP4K4|HGK|KIAA0687|NIK protein taxon:9606 20180719 ARUK-UCL occurs_in(CL:0000312),has_input(UniProtKB:P62330)
- UniProtKB O95999 BCL10 involved_in GO:0043280 PMID:22267217 IMP P B-cell lymphoma/leukemia 10 BCL10|CIPER|CLAP protein taxon:9606 20190502 ARUK-UCL has_input(UniProtKB:Q14790),occurs_in(CL:0000451)
- UniProtKB P00973 OAS1 involved_in GO:0060700 PMID:25275129 IDA P 2'-5'-oligoadenylate synthase 1 OAS1|OIAS protein taxon:9606 20210215 ARUK-UCL part_of(GO:0051607)
- UniProtKB P01034 CST3 involved_in GO:0010466 PMID:18256700 IDA P Cystatin-C CST3 protein taxon:9606 20190227 ARUK-UCL has_input(UniProtKB:P53634),has_input(UniProtKB:P07711)
- UniProtKB P01138 NGF involved_in GO:0043388 PMID:10362258 ISS UniProtKB:P01139 P Beta-nerve growth factor NGF|NGFB protein taxon:9606 20180124 ARUK-UCL has_input(UniProtKB:Q09472),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:P08047),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:Q02447),has_input(UniProtKB:P38936),has_input(CHEBI:4705)
- UniProtKB P01375 TNF acts_upstream_of_or_within GO:0043154 PMID:31124343 IGI RNAcentral:URS0000330617_9606 P Tumor necrosis factor TNF|TNFA|TNFSF2 protein taxon:9606 20200210 ARUK-UCL occurs_in(CL:0000214),part_of(GO:2001234)
- UniProtKB P01375 TNF involved_in GO:0051092 GO_REF:0000024 ISS UniProtKB:P16599 P Tumor necrosis factor TNF|TNFA|TNFSF2 protein taxon:9606 20180927 ARUK-UCL occurs_in(CL:2000043),has_input(UniProtKB:Q04206),positively_regulates(GO:0032635)|occurs_in(CL:0000127),has_input(UniProtKB:Q04206)
- UniProtKB P01579 IFNG involved_in GO:1902948 PMID:19808651 IGI UniProtKB:P05067,UniProtKB:P10636,UniProtKB:P49768 P Interferon gamma IFNG protein taxon:9606 20190430 ARUK-UCL occurs_in(UBERON:0002421)
- UniProtKB P01579 IFNG involved_in GO:1904783 GO_REF:0000024 ISS UniProtKB:P01581 P Interferon gamma IFNG protein taxon:9606 20190318 ARUK-UCL occurs_in(CL:0000540),occurs_in(UBERON:0002181),occurs_in(CL:0000129)
- UniProtKB P01579 IFNG involved_in GO:2000273 GO_REF:0000024 ISS UniProtKB:P01580 P Interferon gamma IFNG protein taxon:9606 20201016 ARUK-UCL has_input(UniProtKB:P25942),occurs_in(CL:0000129)
- UniProtKB P02649 APOE involved_in GO:1905860 PMID:8300609 IDA P Apolipoprotein E APOE protein taxon:9606 20170123 ARUK-UCL has_input(GO:0034361)
- UniProtKB P02786 TFRC involved_in GO:0051092 PMID:23016877 IMP P Transferrin receptor protein 1 TFRC protein taxon:9606 20191126 ARUK-UCL occurs_in(CL:0000066)
- UniProtKB P04156 PRNP involved_in GO:0061098 PMID:24012003 IGI ComplexPortal:CPX-1134,UniProtKB:P41594 P Major prion protein PRNP|ALTPRP|PRIP|PRP protein taxon:9606 20170628 ARUK-UCL has_input(UniProtKB:P06241)
- UniProtKB P04156 PRNP involved_in GO:1902938 PMID:24012003 IGI ComplexPortal:CPX-1134,UniProtKB:P41594 P Major prion protein PRNP|ALTPRP|PRIP|PRP protein taxon:9606 20170628 ARUK-UCL
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:10636900 IDA P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:18728015 IGI UniProtKB:P50993 P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL occurs_in(GO:0005886),part_of(GO:1903408),has_input(UniProtKB:P50993)
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:19542013 IDA P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:20100892 IGI UniProtKB:P50993 P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL occurs_in(GO:0005886),part_of(GO:1903408),has_input(UniProtKB:P50993)
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:20100892 IGI UniProtKB:Q13733 P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL occurs_in(CL:0000019),part_of(GO:1903408),has_input(UniProtKB:Q13733)
- UniProtKB P05026 ATP1B1 involved_in GO:1903408 PMID:23954377 IDA P Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1|ATP1B protein taxon:9606 20200717 ARUK-UCL
- UniProtKB P05067 APP NOT|involved_in GO:1905598 PMID:20005821 IGI UniProtKB:P35951,UniProtKB:P49768 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170601 ARUK-UCL
- UniProtKB P05067 APP involved_in GO:0032092 PMID:24052308 IGI UniProtKB:P49768,UniProtKB:P97484 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170725 ARUK-UCL has_input(UniProtKB:P97484),has_input(UniProtKB:P18760),occurs_in(UBERON:0001890)
- UniProtKB P05067 APP involved_in GO:0051091 PMID:23921129 IGI ComplexPortal:CPX-1134 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230517 ARUK-UCL occurs_in(CL:0010012),part_of(GO:1904646),has_input(UniProtKB:P05412)
- UniProtKB P05067 APP involved_in GO:2000310 PMID:17360908 TAS P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170217 ARUK-UCL occurs_in(CL:0010012)
- UniProtKB P05107 ITGB2 involved_in GO:2000363 PMID:18981141 NAS P Integrin beta-2 ITGB2|CD18|MFI7 protein taxon:9606 20210429 ARUK-UCL occurs_in(UBERON:0001891),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)
- UniProtKB P05112 IL4 involved_in GO:0042976 PMID:12574355 IGI UniProtKB:P08575 P Interleukin-4 IL4 protein taxon:9606 20180724 ARUK-UCL has_input(UniProtKB:P23458)|has_input(UniProtKB:P52333)
- UniProtKB P05556 ITGB1 acts_upstream_of_or_within GO:1901979 GO_REF:0000024 ISS UniProtKB:P09055 P Integrin beta-1 ITGB1|FNRB|MDF2|MSK12 protein taxon:9606 20200116 ARUK-UCL occurs_in(UBERON:0003528),occurs_in(CL:0000127)
- UniProtKB P06213 INSR involved_in GO:0006468 PMID:19188609 TAS P Insulin receptor INSR protein taxon:9606 20170523 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB P06239 LCK involved_in GO:0018108 PMID:11606584 IMP P Tyrosine-protein kinase Lck LCK protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB P06241 FYN involved_in GO:0018108 PMID:11606584 IMP P Tyrosine-protein kinase Fyn FYN protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB P06241 FYN involved_in GO:0018108 PMID:27520374 IMP P Tyrosine-protein kinase Fyn FYN protein taxon:9606 20181219 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:P10636),part_of(GO:1904646)
- UniProtKB P06241 FYN involved_in GO:0018108 PMID:27525436 ISS UniProtKB:Q62844 P Tyrosine-protein kinase Fyn FYN protein taxon:9606 20180509 ARUK-UCL has_input(UniProtKB:Q9NPH5),occurs_in(CL:0000746),negatively_regulates(GO:1903409)
- UniProtKB P06241 FYN involved_in GO:2001056 PMID:17526495 ISS UniProtKB:Q62844 P Tyrosine-protein kinase Fyn FYN protein taxon:9606 20171218 ARUK-UCL part_of(GO:1905232),part_of(GO:1905430),occurs_in(GO:0009986)
- UniProtKB P06400 RB1 involved_in GO:0071901 PMID:24027266 ISS UniProtKB:P33568 P Retinoblastoma-associated protein RB1 protein taxon:9606 20190307 ARUK-UCL occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)
- UniProtKB P06400 RB1 involved_in GO:1902948 PMID:24027266 ISS UniProtKB:P33568 P Retinoblastoma-associated protein RB1 protein taxon:9606 20190307 ARUK-UCL occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)
- UniProtKB P06727 APOA4 involved_in GO:1905920 PMID:1935934 IDA P Apolipoprotein A-IV APOA4 protein taxon:9606 20220217 ARUK-UCL
- UniProtKB P07339 CTSD involved_in GO:0043280 PMID:12107093 IDA P Cathepsin D CTSD|CPSD protein taxon:9606 20190306 ARUK-UCL
- UniProtKB P07384 CAPN1 involved_in GO:2000310 PMID:17526495 TAS P Calpain-1 catalytic subunit CAPN1|CANPL1|PIG30 protein taxon:9606 20171218 ARUK-UCL has_input(UniProtKB:Q13224),occurs_in(CL:0002608)
- UniProtKB P07550 ADRB2 involved_in GO:0071902 PMID:20395454 IGI ComplexPortal:CPX-1070 P Beta-2 adrenergic receptor ADRB2|ADRB2R|B2AR protein taxon:9606 20170525 ARUK-UCL part_of(GO:0010739),has_input(UniProtKB:P42261),positively_regulates(GO:0004971)
- UniProtKB P07550 ADRB2 involved_in GO:2000481 PMID:20395454 TAS P Beta-2 adrenergic receptor ADRB2|ADRB2R|B2AR protein taxon:9606 20170525 ARUK-UCL has_input(UniProtKB:Q05586),part_of(GO:1990911)
- UniProtKB P07550 ADRB2 involved_in GO:2000969 PMID:20395454 IGI ComplexPortal:CPX-1070 P Beta-2 adrenergic receptor ADRB2|ADRB2R|B2AR protein taxon:9606 20170525 ARUK-UCL part_of(GO:0010739),has_input(UniProtKB:P42261)
- UniProtKB P07900 HSP90AA1 involved_in GO:1902949 PMID:19363271 IDA P Heat shock protein HSP 90-alpha HSP90AA1|HSP90A|HSPC1|HSPCA protein taxon:9606 20180226 ARUK-UCL has_input(UniProtKB:P49841)
- UniProtKB P07948 LYN involved_in GO:1902961 PMID:24217950 IMP P Tyrosine-protein kinase Lyn LYN|JTK8 protein taxon:9606 20170621 ARUK-UCL
- UniProtKB P08238 HSP90AB1 involved_in GO:1902949 GO_REF:0000111 IC GO:1904031 P Heat shock protein HSP 90-beta HSP90AB1|HSP90B|HSPC2|HSPCB protein taxon:9606 20180226 ARUK-UCL has_input(UniProtKB:Q00535)
- UniProtKB P08238 HSP90AB1 involved_in GO:1904031 PMID:17517623 ISS UniProtKB:P34058 P Heat shock protein HSP 90-beta HSP90AB1|HSP90B|HSPC2|HSPCB protein taxon:9606 20180226 ARUK-UCL has_input(UniProtKB:Q00535),occurs_in(CL:0010012)
- UniProtKB P08575 PTPRC involved_in GO:0061097 PMID:12100025 IDA P Receptor-type tyrosine-protein phosphatase C PTPRC|CD45 protein taxon:9606 20180725 ARUK-UCL occurs_in(CL:0000096),has_input(UniProtKB:P06239)
- UniProtKB P08575 PTPRC involved_in GO:0061099 GO_REF:0000024 ISS UniProtKB:P06800 P Receptor-type tyrosine-protein phosphatase C PTPRC|CD45 protein taxon:9606 20180723 ARUK-UCL occurs_in(CL:0000084),occurs_in(GO:0045121),has_input(UniProtKB:O54957)
- UniProtKB P08575 PTPRC involved_in GO:1903615 GO_REF:0000024 ISS UniProtKB:P06800 P Receptor-type tyrosine-protein phosphatase C PTPRC|CD45 protein taxon:9606 20180723 ARUK-UCL occurs_in(CL:0000084)
- UniProtKB P0DP24 CALM2 involved_in GO:1901020 GO_REF:0000024 ISS UniProtKB:P0DP27 P Calmodulin-2 CALM2|CAM2|CAMB protein taxon:9606 20210421 ARUK-UCL has_input(UniProtKB:Q8NFF2),causally_upstream_of(GO:0050848)
- UniProtKB P10636 MAPT involved_in GO:0006475 PMID:28386764 TAS P Microtubule-associated protein tau MAPT|MAPTL|MTBT1|TAU protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB P11137 MAP2 involved_in GO:1904527 GO_REF:0000024 ISS UniProtKB:P15146 P Microtubule-associated protein 2 MAP2 protein taxon:9606 20210816 ARUK-UCL has_input(UniProtKB:P33176)
- UniProtKB P11215 ITGAM involved_in GO:2000363 GO_REF:0000024 ISS UniProtKB:P05555 P Integrin alpha-M ITGAM|CD11B|CR3A protein taxon:9606 20230605 ARUK-UCL occurs_in(UBERON:0001891),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)|occurs_in(UBERON:0001891),occurs_in(CL:0000540),has_output(CHEBI:15551),part_of(GO:0033554)
- UniProtKB P12314 FCGR1A involved_in GO:0061098 PMID:10556798 IMP P High affinity immunoglobulin gamma Fc receptor I FCGR1A|FCG1|FCGR1|IGFR1 protein taxon:9606 20190404 ARUK-UCL
- UniProtKB P12931 SRC involved_in GO:0018108 PMID:11606584 IMP P Proto-oncogene tyrosine-protein kinase Src SRC|SRC1 protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB P12931 SRC involved_in GO:0018108 PMID:20018849 NAS P Proto-oncogene tyrosine-protein kinase Src SRC|SRC1 protein taxon:9606 20180719 ARUK-UCL has_input(UniProtKB:Q05397)
- UniProtKB P12931 SRC involved_in GO:1903997 PMID:20018849 NAS P Proto-oncogene tyrosine-protein kinase Src SRC|SRC1 protein taxon:9606 20180719 ARUK-UCL has_input(UniProtKB:Q05397)
- UniProtKB P13500 CCL2 involved_in GO:1904783 GO_REF:0000024 ISS UniProtKB:P14844 P C-C motif chemokine 2 CCL2|MCP1|SCYA2 protein taxon:9606 20190318 ARUK-UCL occurs_in(CL:0000540),occurs_in(UBERON:0002181)
- UniProtKB P16615 ATP2A2 involved_in GO:1900121 PMID:18068335 IMP P Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2|ATP2B protein taxon:9606 20191001 ARUK-UCL occurs_in(CL:0000233),part_of(GO:0006874)
- UniProtKB P16671 CD36 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:O00206,UniProtKB:P05067-PRO_0000000092,UniProtKB:Q9Y2C9 P Platelet glycoprotein 4 CD36|GP3B|GP4 protein taxon:9606 20170517 ARUK-UCL
- UniProtKB P16671 CD36 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:O00206,UniProtKB:Q9Y2C9 P Platelet glycoprotein 4 CD36|GP3B|GP4 protein taxon:9606 20170517 ARUK-UCL occurs_in(CL:0000235),positively_regulates(GO:0002269),part_of(GO:0071404)
- UniProtKB P16885 PLCG2 acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q8CIH5 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P05412)
- UniProtKB P16885 PLCG2 acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q8CIH5 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q12968)
- UniProtKB P16885 PLCG2 acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q8CIH5 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q13469)
- UniProtKB P16885 PLCG2 involved_in GO:0051091 GO_REF:0000024 ISS UniProtKB:P24135 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P01100),occurs_in(CL:0000182),part_of(GO:1902808)
- UniProtKB P16885 PLCG2 involved_in GO:0051091 GO_REF:0000024 ISS UniProtKB:P24135 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P01106),occurs_in(CL:0000182),part_of(GO:1902808)
- UniProtKB P16885 PLCG2 involved_in GO:0051091 GO_REF:0000024 ISS UniProtKB:P24135 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P05412),occurs_in(CL:0000182),part_of(GO:1902808)
- UniProtKB P16885 PLCG2 involved_in GO:0051091 GO_REF:0000024 ISS UniProtKB:P24135 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:Q00653),occurs_in(CL:0000182),part_of(GO:1902808)
- UniProtKB P16885 PLCG2 involved_in GO:0051092 GO_REF:0000024 ISS UniProtKB:Q8CIH5 P 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 protein taxon:9606 20210524 ARUK-UCL occurs_in(CL:0000451),part_of(GO:1990840)
- UniProtKB P17252 PRKCA involved_in GO:0018105 PMID:26078884 TAS P Protein kinase C alpha type PRKCA|PKCA|PRKACA protein taxon:9606 20170814 ARUK-UCL has_input(UniProtKB:Q05586)
- UniProtKB P17252 PRKCA involved_in GO:0018107 PMID:16717194 ISS UniProtKB:P05696 P Protein kinase C alpha type PRKCA|PKCA|PRKACA protein taxon:9606 20180508 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:Q7KZI7),negatively_regulates(GO:0018105)
- UniProtKB P17612 PRKACA involved_in GO:0018105 PMID:26078884 TAS P cAMP-dependent protein kinase catalytic subunit alpha PRKACA|PKACA protein taxon:9606 20170814 ARUK-UCL has_input(UniProtKB:Q05586)
- UniProtKB P17931 LGALS3 involved_in GO:1903614 PMID:24846175 IC GO:0031334 P Galectin-3 LGALS3|MAC2 protein taxon:9606 20191216 ARUK-UCL has_input(UniProtKB:O14522)
- UniProtKB P17947 SPI1 involved_in GO:0032088 PMID:28362429 IDA P Transcription factor PU.1 SPI1 protein taxon:9606 20201217 ARUK-UCL happens_during(GO:0002357),has_input(UniProtKB:Q04206)
- UniProtKB P17947 SPI1 involved_in GO:0051090 GO_REF:0000024 ISS UniProtKB:P17433 P Transcription factor PU.1 SPI1 protein taxon:9606 20201202 ARUK-UCL
- UniProtKB P18031 PTPN1 acts_upstream_of GO:0043507 GO_REF:0000024 ISS UniProtKB:P35821 P Tyrosine-protein phosphatase non-receptor type 1 PTPN1|PTP1B protein taxon:9606 20210421 ARUK-UCL part_of(GO:0034976)
- UniProtKB P18146 EGR1 involved_in GO:1902949 GO_REF:0000024 ISS UniProtKB:A0A0H2UHR3 P Early growth response protein 1 EGR1|KROX24|ZNF225 protein taxon:9606 20230301 ARUK-UCL occurs_in(CL:0010012)
- UniProtKB P19784 CSNK2A2 involved_in GO:0018105 PMID:28031292 IDA P Casein kinase II subunit alpha' CSNK2A2|CK2A2 protein taxon:9606 20180517 ARUK-UCL has_input(UniProtKB:P25686-1)|has_input(UniProtKB:P25686-2)
- UniProtKB P20138 CD33 involved_in GO:1903615 PMID:10556798 IMP P Myeloid cell surface antigen CD33 CD33|SIGLEC3 protein taxon:9606 20190403 ARUK-UCL has_input(UniProtKB:P29351)
- UniProtKB P20309 CHRM3 acts_upstream_of_or_within GO:0032412 PMID:17478539 IDA P Muscarinic acetylcholine receptor M3 CHRM3 protein taxon:9606 20200115 ARUK-UCL occurs_in(CL:0011108),occurs_in(UBERON:0013485),part_of(GO:1905144),has_input(UniProtKB:P55011),occurs_in(GO:0009925)
- UniProtKB P20309 CHRM3 acts_upstream_of_or_within GO:0032412 PMID:17478539 IDA P Muscarinic acetylcholine receptor M3 CHRM3 protein taxon:9606 20200115 ARUK-UCL occurs_in(CL:0011108),occurs_in(UBERON:0013485),part_of(GO:1905144),has_input(UniProtKB:P55011),occurs_in(GO:0016328)
- UniProtKB P20827 EFNA1 involved_in GO:0061098 PMID:24217950 IGI UniProtKB:P54764 P Ephrin-A1 EFNA1|EPLG1|LERK1|TNFAIP4 protein taxon:9606 20170621 ARUK-UCL has_input(UniProtKB:P07948)
- UniProtKB P20827 EFNA1 involved_in GO:1902961 PMID:24217950 IGI UniProtKB:P54764 P Ephrin-A1 EFNA1|EPLG1|LERK1|TNFAIP4 protein taxon:9606 20170620 ARUK-UCL
- UniProtKB P21730 C5AR1 involved_in GO:1902947 GO_REF:0000024 ISS UniProtKB:P30993 P C5a anaphylatoxin chemotactic receptor 1 C5AR1|C5AR|C5R1 protein taxon:9606 20190104 ARUK-UCL occurs_in(UBERON:0002421)
- UniProtKB P27448 MARK3 involved_in GO:0018105 PMID:9543386 IDA P MAP/microtubule affinity-regulating kinase 3 MARK3|CTAK1|EMK2 protein taxon:9606 20180328 ARUK-UCL has_input(UniProtKB:P30307),positively_regulates(GO:0005515)
- UniProtKB P27448 MARK3 involved_in GO:0032092 PMID:9543386 IDA P MAP/microtubule affinity-regulating kinase 3 MARK3|CTAK1|EMK2 protein taxon:9606 20180328 ARUK-UCL has_input(UniProtKB:P30307),has_input(UniProtKB:P63104)
- UniProtKB P27448 MARK3 involved_in GO:0036289 PMID:9543386 IDA P MAP/microtubule affinity-regulating kinase 3 MARK3|CTAK1|EMK2 protein taxon:9606 20180328 ARUK-UCL has_input(UniProtKB:P27448)
- UniProtKB P28482 MAPK1 involved_in GO:0006468 PMID:11404397 TAS P Mitogen-activated protein kinase 1 MAPK1|ERK2|PRKM1|PRKM2 protein taxon:9606 20170210 ARUK-UCL has_input(UniProtKB:P51812)
- UniProtKB P29323 EPHB2 acts_upstream_of GO:0006469 GO_REF:0000024 ISS UniProtKB:P54763 P Ephrin type-B receptor 2 EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5 protein taxon:9606 20210421 ARUK-UCL
- UniProtKB P29323 EPHB2 involved_in GO:0018108 GO_REF:0000024 ISS UniProtKB:P54763 P Ephrin type-B receptor 2 EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5 protein taxon:9606 20170620 ARUK-UCL has_input(UniProtKB:Q05586)
- UniProtKB P29323 EPHB2 involved_in GO:1904782 GO_REF:0000024 ISS UniProtKB:P54763 P Ephrin type-B receptor 2 EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5 protein taxon:9606 20170620 ARUK-UCL causally_upstream_of(GO:1900272),occurs_in(CL:2000089)
- UniProtKB P29323 EPHB2 involved_in GO:1904783 GO_REF:0000024 ISS UniProtKB:P54763 P Ephrin type-B receptor 2 EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5 protein taxon:9606 20170620 ARUK-UCL causally_upstream_of(GO:1900273),occurs_in(CL:2000089)
- UniProtKB P30990 NTS acts_upstream_of GO:0051092 PMID:21806946 IDA P Neurotensin/neuromedin N NTS protein taxon:9606 20210720 ARUK-UCL causally_upstream_of(GO:0010628)
- UniProtKB P31749 AKT1 involved_in GO:0032091 PMID:18292230 IMP P RAC-alpha serine/threonine-protein kinase AKT1|PKB|RAC protein taxon:9606 20180201 ARUK-UCL has_input(UniProtKB:Q9UNE7),has_input(UniProtKB:P10636)
- UniProtKB P31749 AKT1 involved_in GO:0071901 PMID:28386764 TAS P RAC-alpha serine/threonine-protein kinase AKT1|PKB|RAC protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P49841)
- UniProtKB P31994 FCGR2B involved_in GO:0010469 PMID:26683154 TAS P Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B|CD32|FCG2|IGFR2 protein taxon:9606 20170614 ARUK-UCL
- UniProtKB P32418 SLC8A1 acts_upstream_of_or_within GO:0071901 GO_REF:0000024 ISS UniProtKB:P70414 P Sodium/calcium exchanger 1 SLC8A1|CNC|NCX1 protein taxon:9606 20191210 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)
- UniProtKB P35222 CTNNB1 acts_upstream_of GO:0051973 GO_REF:0000024 ISS UniProtKB:Q02248 P Catenin beta-1 CTNNB1|CTNNB|OK/SW-cl.35|PRO2286 protein taxon:9606 20210113 ARUK-UCL occurs_in(CL:0002322)
- UniProtKB P35638 DDIT3 acts_upstream_of_or_within GO:0032088 PMID:24038088 IDA P DNA damage-inducible transcript 3 protein DDIT3|CHOP|CHOP10|GADD153 protein taxon:9606 20200527 ARUK-UCL occurs_in(CL:0000084)
- UniProtKB P35638 DDIT3 involved_in GO:0051091 GO_REF:0000024 ISS UniProtKB:P35639 P DNA damage-inducible transcript 3 protein DDIT3|CHOP|CHOP10|GADD153 protein taxon:9606 20190715 ARUK-UCL
- UniProtKB P36544 CHRNA7 involved_in GO:1905920 GO_REF:0000024 ISS UniProtKB:P49582 P Neuronal acetylcholine receptor subunit alpha-7 CHRNA7|NACHRA7 protein taxon:9606 20170213 ARUK-UCL happens_during(UBERON:0018241),occurs_in(UBERON:0002421),has_input(UniProtKB:Q03059)|happens_during(UBERON:0018241),occurs_in(UBERON:0002743),has_input(UniProtKB:Q03059)
- UniProtKB P37840 SNCA involved_in GO:0006469 PMID:30194957 TAS P Alpha-synuclein SNCA|NACP|PARK1 protein taxon:9606 20191218 ARUK-UCL
- UniProtKB P37840 SNCA involved_in GO:0022898 PMID:18331289 IGI UniProtKB:P60709 P Alpha-synuclein SNCA|NACP|PARK1 protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569)
- UniProtKB P40763 STAT3 involved_in GO:0051092 GO_REF:0000024 ISS UniProtKB:P52631 P Signal transducer and activator of transcription 3 STAT3|APRF protein taxon:9606 20180927 ARUK-UCL has_input(UniProtKB:Q04206),positively_regulates(GO:0032635),occurs_in(CL:2000043)
- UniProtKB P41134 ID1 involved_in GO:0043433 PMID:7665172 IDA P DNA-binding protein inhibitor ID-1 ID1|BHLHB24|ID protein taxon:9606 20201127 ARUK-UCL
- UniProtKB P41217 CD200 involved_in GO:0032088 PMID:26670206 IDA P OX-2 membrane glycoprotein CD200|MOX1|MOX2|My033 protein taxon:9606 20180718 ARUK-UCL occurs_in(CL:0000235),part_of(GO:0071222),part_of(GO:0071346)
- UniProtKB P41217 CD200 involved_in GO:0032793 PMID:26670206 IDA P OX-2 membrane glycoprotein CD200|MOX1|MOX2|My033 protein taxon:9606 20180718 ARUK-UCL occurs_in(CL:0000235),part_of(GO:0071222),part_of(GO:0071346)
- UniProtKB P41217 CD200 involved_in GO:0150072 PMID:26670206 IGI UniProtKB:P21272 P OX-2 membrane glycoprotein CD200|MOX1|MOX2|My033 protein taxon:9606 20180730 ARUK-UCL has_input(UniProtKB:P05089),occurs_in(CL:0000235)
- UniProtKB P41217 CD200 involved_in GO:0150074 PMID:26670206 IGI UniProtKB:P21272 P OX-2 membrane glycoprotein CD200|MOX1|MOX2|My033 protein taxon:9606 20180730 ARUK-UCL has_input(UniProtKB:P21980),occurs_in(CL:0000235)
- UniProtKB P41594 GRM5 involved_in GO:0061098 GO_REF:0000024 ISS UniProtKB:P31424 P Metabotropic glutamate receptor 5 GRM5|GPRC1E|MGLUR5 protein taxon:9606 20170628 ARUK-UCL has_input(UniProtKB:P06241)
- UniProtKB P41594 GRM5 involved_in GO:0061098 GO_REF:0000024 ISS UniProtKB:Q3UVX5 P Metabotropic glutamate receptor 5 GRM5|GPRC1E|MGLUR5 protein taxon:9606 20170628 ARUK-UCL has_input(UniProtKB:P39688),occurs_in(CL:0010012)
- UniProtKB P41594 GRM5 involved_in GO:1902938 PMID:24012003 IGI ComplexPortal:CPX-1134,UniProtKB:P04156 P Metabotropic glutamate receptor 5 GRM5|GPRC1E|MGLUR5 protein taxon:9606 20170628 ARUK-UCL
- UniProtKB P41597 CCR2 involved_in GO:1904783 GO_REF:0000024 ISS UniProtKB:O55193 P C-C chemokine receptor type 2 CCR2|CMKBR2 protein taxon:9606 20190318 ARUK-UCL occurs_in(CL:0000540),occurs_in(UBERON:0002181)
- UniProtKB P42345 MTOR involved_in GO:0032516 PMID:28386764 TAS P Serine/threonine-protein kinase mTOR MTOR|FRAP|FRAP1|FRAP2|RAFT1|RAPT1 protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P67775)
- UniProtKB P42858 HTT involved_in GO:2000479 PMID:21768291 IMP P Huntingtin HTT|HD|IT15 protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:Q13131),occurs_in(UBERON:0002435)
- UniProtKB P43405 SYK involved_in GO:0018108 PMID:11606584 IDA P Tyrosine-protein kinase SYK SYK protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB P43405 SYK involved_in GO:0018108 PMID:11606584 IDA P Tyrosine-protein kinase SYK SYK protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P19174),part_of(GO:0035556)
- UniProtKB P43405 SYK involved_in GO:0018108 PMID:11606584 IMP P Tyrosine-protein kinase SYK SYK protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:Q8WV28),part_of(GO:0035556)
- UniProtKB P43405 SYK involved_in GO:0018108 PMID:14656219 IGI UniProtKB:P16885 P Tyrosine-protein kinase SYK SYK protein taxon:9606 20210308 ARUK-UCL occurs_in(CL:0000233),has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB P43405 SYK involved_in GO:0018108 PMID:15509800 IMP P Tyrosine-protein kinase SYK SYK protein taxon:9606 20210224 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0050853)
- UniProtKB P43405 SYK involved_in GO:0043280 PMID:22267217 IMP P Tyrosine-protein kinase SYK SYK protein taxon:9606 20190502 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:Q14790)
- UniProtKB P47901 AVPR1B involved_in GO:0007202 PMID:9322919 IDA P Vasopressin V1b receptor AVPR1B|AVPR3|VPR3 protein taxon:9606 20191024 ARUK-UCL
- UniProtKB P47901 AVPR1B involved_in GO:0032430 PMID:9322919 IDA P Vasopressin V1b receptor AVPR1B|AVPR3|VPR3 protein taxon:9606 20191024 ARUK-UCL
- UniProtKB P48067 SLC6A9 acts_upstream_of GO:1904782 GO_REF:0000024 ISS UniProtKB:P28571 P Sodium- and chloride-dependent glycine transporter 1 SLC6A9 protein taxon:9606 20200612 ARUK-UCL occurs_in(CL:1001571)
- UniProtKB P49238 CX3CR1 involved_in GO:0051092 GO_REF:0000024 ISS UniProtKB:P35411 P CX3C chemokine receptor 1 CX3CR1|CMKBRL1|GPR13 protein taxon:9606 20180605 ARUK-UCL occurs_in(CL:0002608)
- UniProtKB P49768 PSEN1 NOT|involved_in GO:1905598 PMID:20005821 IGI UniProtKB:P05067,UniProtKB:P35951 P Presenilin-1 PSEN1|AD3|PS1|PSNL1 protein taxon:9606 20170601 ARUK-UCL
- UniProtKB P49768 PSEN1 involved_in GO:0032092 PMID:24052308 IGI UniProtKB:P49768,UniProtKB:P97484 P Presenilin-1 PSEN1|AD3|PS1|PSNL1 protein taxon:9606 20170725 ARUK-UCL has_input(UniProtKB:P97484),has_input(UniProtKB:P18760),occurs_in(UBERON:0001890)
- UniProtKB P49840 GSK3A involved_in GO:0018107 PMID:25897075 IDA P Glycogen synthase kinase-3 alpha GSK3A protein taxon:9606 20171120 ARUK-UCL has_input(UniProtKB:Q6R327)
- UniProtKB P49841 GSK3B involved_in GO:0018105 PMID:17139249 IDA P Glycogen synthase kinase-3 beta GSK3B protein taxon:9606 20171109 ARUK-UCL has_input(UniProtKB:Q96G01),regulates(GO:0000226),regulates(GO:0045505)
- UniProtKB P49841 GSK3B involved_in GO:0018105 PMID:30556160 IGI RNAcentral:URS0000565C8D_9606 P Glycogen synthase kinase-3 beta GSK3B protein taxon:9606 20210720 ARUK-UCL has_input(UniProtKB:P10636),occurs_in(UBERON:0000955)
- UniProtKB P49841 GSK3B involved_in GO:0018107 PMID:17139249 IDA P Glycogen synthase kinase-3 beta GSK3B protein taxon:9606 20171017 ARUK-UCL has_input(UniProtKB:Q96G01),regulates(GO:0000226),regulates(GO:0045505)
- UniProtKB P49841 GSK3B involved_in GO:0018107 PMID:25897075 IDA P Glycogen synthase kinase-3 beta GSK3B protein taxon:9606 20171120 ARUK-UCL has_input(UniProtKB:Q6R327)
- UniProtKB P49841 GSK3B involved_in GO:0032515 PMID:28386764 TAS P Glycogen synthase kinase-3 beta GSK3B protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P67775)
- UniProtKB P51451 BLK involved_in GO:0032092 PMID:23555801 IMP P Tyrosine-protein kinase Blk BLK protein taxon:9606 20210420 ARUK-UCL has_input(UniProtKB:P16885),has_input(UniProtKB:Q8NDB2),part_of(GO:0050853)
- UniProtKB P51812 RPS6KA3 involved_in GO:0018105 PMID:11404397 TAS P Ribosomal protein S6 kinase alpha-3 RPS6KA3|ISPK1|MAPKAPK1B|RSK2 protein taxon:9606 20170210 ARUK-UCL has_input(UniProtKB:P16220)
- UniProtKB P52797 EFNA3 involved_in GO:1902961 PMID:24217950 IGI UniProtKB:P54764 P Ephrin-A3 EFNA3|EFL2|EPLG3|LERK3 protein taxon:9606 20170620 ARUK-UCL
- UniProtKB P53041 PPP5C involved_in GO:0035970 PMID:16262633 TAS P Serine/threonine-protein phosphatase 5 PPP5C|PPP5 protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P53041 PPP5C involved_in GO:0070262 PMID:16262633 TAS P Serine/threonine-protein phosphatase 5 PPP5C|PPP5 protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P53794 SLC5A3 acts_upstream_of_or_within GO:0043085 GO_REF:0000024 ISS UniProtKB:Q80WA5 P Sodium/myo-inositol cotransporter SLC5A3 protein taxon:9606 20200329 ARUK-UCL has_input(UniProtKB:P04839)
- UniProtKB P54710 FXYD2 involved_in GO:1903408 GO_REF:0000024 ISS UniProtKB:Q58K79 P Sodium/potassium-transporting ATPase subunit gamma FXYD2|ATP1C|ATP1G1 protein taxon:9606 20201111 ARUK-UCL has_input(UniProtKB:P05023)
- UniProtKB P54764 EPHA4 involved_in GO:0061098 GO_REF:0000024 ISS UniProtKB:Q03137 P Ephrin type-A receptor 4 EPHA4|HEK8|SEK|TYRO1 protein taxon:9606 20170627 ARUK-UCL occurs_in(CL:0002608),has_input(UniProtKB:P00519)
- UniProtKB P54764 EPHA4 involved_in GO:1902961 PMID:24217950 IGI UniProtKB:P20827|UniProtKB:P52797 P Ephrin type-A receptor 4 EPHA4|HEK8|SEK|TYRO1 protein taxon:9606 20170620 ARUK-UCL
- UniProtKB P57103 SLC8A3 acts_upstream_of_or_within GO:0071901 GO_REF:0000024 ISS UniProtKB:S4R2P9 P Sodium/calcium exchanger 3 SLC8A3|NCX3 protein taxon:9606 20191210 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)
- UniProtKB P60709 ACTB involved_in GO:0000079 GO_REF:0000024 ISS UniProtKB:P60711 P Actin, cytoplasmic 1 ACTB protein taxon:9606 20180514 ARUK-UCL has_input(UniProtKB:Q00535),happens_during(GO:0030036)
- UniProtKB P60709 ACTB involved_in GO:0022898 PMID:18331289 IGI UniProtKB:P37840 P Actin, cytoplasmic 1 ACTB protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569)
- UniProtKB P60709 ACTB involved_in GO:0022898 PMID:18331289 ISS UniProtKB:P60711 P Actin, cytoplasmic 1 ACTB protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569),occurs_in(CL:0000540),occurs_in(UBERON:0001870)
- UniProtKB P60709 ACTB involved_in GO:0022898 PMID:18331289 ISS UniProtKB:P60711 P Actin, cytoplasmic 1 ACTB protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569),occurs_in(CL:0000540),occurs_in(UBERON:0002148)
- UniProtKB P60709 ACTB involved_in GO:0032091 GO_REF:0000024 ISS UniProtKB:P60710 P Actin, cytoplasmic 1 ACTB protein taxon:9606 20171103 ARUK-UCL has_input(UniProtKB:Q15078),has_input(UniProtKB:Q00535)
- UniProtKB P62136 PPP1CA involved_in GO:0035970 PMID:16262633 TAS P Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA|PPP1A protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P62136 PPP1CA involved_in GO:0070262 PMID:16262633 TAS P Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA|PPP1A protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P62714 PPP2CB involved_in GO:0032088 PMID:28159925 IGI UniProtKB:Q04206 P Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB protein taxon:9606 20210716 ARUK-UCL occurs_in(CL:0000134)
- UniProtKB P62714 PPP2CB involved_in GO:0035970 PMID:16262633 TAS P Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P62714 PPP2CB involved_in GO:0070262 PMID:16262633 TAS P Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P62714 PPP2CB involved_in GO:1904528 GO_REF:0000024 ISS UniProtKB:P62716 P Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB protein taxon:9606 20171208 ARUK-UCL has_input(UniProtKB:P46821)
- UniProtKB P67775 PPP2CA involved_in GO:0035970 PMID:16262633 TAS P Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P67775 PPP2CA involved_in GO:0070262 PMID:16262633 TAS P Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA protein taxon:9606 20171207 ARUK-UCL
- UniProtKB P67775 PPP2CA involved_in GO:1904526 PMID:28386764 NAS P Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB P67775 PPP2CA involved_in GO:1904528 GO_REF:0000024 ISS UniProtKB:P63331 P Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA protein taxon:9606 20171208 ARUK-UCL has_input(UniProtKB:P46821)|has_input(UniProtKB:P11137)
- UniProtKB P68400 CSNK2A1 involved_in GO:0018105 PMID:28031292 IDA P Casein kinase II subunit alpha CSNK2A1|CK2A1 protein taxon:9606 20180517 ARUK-UCL has_input(UniProtKB:P25686-1)|has_input(UniProtKB:P25686-2)
- UniProtKB P78352 DLG4 involved_in GO:0061098 PMID:17526495 ISS UniProtKB:P31016 P Disks large homolog 4 DLG4|PSD95 protein taxon:9606 20171218 ARUK-UCL
- UniProtKB P78352 DLG4 involved_in GO:0061098 PMID:17526495 TAS P Disks large homolog 4 DLG4|PSD95 protein taxon:9606 20171218 ARUK-UCL has_input(UniProtKB:P06241),causally_upstream_of(GO:2000310)
- UniProtKB P78423 CX3CL1 involved_in GO:0051092 PMID:10869418 IGI UniProtKB:P35411 P Fractalkine CX3CL1|FKN|NTT|SCYD1|A-152E5.2 protein taxon:9606 20180605 ARUK-UCL occurs_in(CL:0002608)
- UniProtKB Q00535 CDK5 involved_in GO:0006468 PMID:17491008 TAS P Cyclin-dependent kinase 5 CDK5|CDKN5|PSSALRE protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:P46821)|has_input(UniProtKB:P11137)|has_input(UniProtKB:P10636)|has_input(UniProtKB:O43602)
- UniProtKB Q00535 CDK5 involved_in GO:0018105 GO_REF:0000024 ISS UniProtKB:P49615 P Cyclin-dependent kinase 5 CDK5|CDKN5|PSSALRE protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:Q13224),occurs_in(UBERON:0002421),regulates(GO:0072659)
- UniProtKB Q00535 CDK5 involved_in GO:0018107 GO_REF:0000024 ISS UniProtKB:P49615 P Cyclin-dependent kinase 5 CDK5|CDKN5|PSSALRE protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:Q9UD71),occurs_in(UBERON:0002421)
- UniProtKB Q00613 HSF1 involved_in GO:0051091 PMID:24504023 IMP P Heat shock factor protein 1 HSF1|HSTF1 protein taxon:9606 20201211 ARUK-UCL has_input(UniProtKB:P17947),happens_during(GO:0030225)
- UniProtKB Q03135 CAV1 involved_in GO:0051092 PMID:23319823 IMP P Caveolin-1 CAV1|CAV protein taxon:9606 20181203 ARUK-UCL
- UniProtKB Q05586 GRIN1 involved_in GO:2001056 PMID:17526495 ISS UniProtKB:P35439 P Glutamate receptor ionotropic, NMDA 1 GRIN1|NMDAR1 protein taxon:9606 20171218 ARUK-UCL occurs_in(CL:0002608)
- UniProtKB Q06187 BTK involved_in GO:0018108 PMID:11606584 IDA P Tyrosine-protein kinase BTK BTK|AGMX1|ATK|BPK protein taxon:9606 20210216 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB Q06187 BTK involved_in GO:0018108 PMID:14656219 IGI UniProtKB:P16885 P Tyrosine-protein kinase BTK BTK|AGMX1|ATK|BPK protein taxon:9606 20210308 ARUK-UCL occurs_in(CL:0000233),has_input(UniProtKB:P16885),part_of(GO:0035556)
- UniProtKB Q06187 BTK involved_in GO:0018108 PMID:15509800 IDA P Tyrosine-protein kinase BTK BTK|AGMX1|ATK|BPK protein taxon:9606 20210224 ARUK-UCL has_input(UniProtKB:P16885),part_of(GO:0050853)
- UniProtKB Q07954 LRP1 acts_upstream_of GO:1905049 PMID:26781079 IC GO:0006898 P Prolow-density lipoprotein receptor-related protein 1 LRP1|A2MR|APR protein taxon:9606 20190624 ARUK-UCL has_input(UniProtKB:P14780),occurs_in(CL:0000359)
- UniProtKB Q07954 LRP1 involved_in GO:0032092 PMID:23386614 IGI UniProtKB:P04925 P Prolow-density lipoprotein receptor-related protein 1 LRP1|A2MR|APR protein taxon:9606 20170626 ARUK-UCL has_input(ComplexPortal:CPX-1134),has_input(UniProtKB:P04925)
- UniProtKB Q09328 MGAT5 involved_in GO:1903614 PMID:24846175 IDA P Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A MGAT5|GGNT5 protein taxon:9606 20180803 ARUK-UCL has_input(UniProtKB:O14522)
- UniProtKB Q09472 EP300 involved_in GO:0018394 PMID:23811396 IDA P Histone acetyltransferase p300 EP300|P300 protein taxon:9606 20201201 ARUK-UCL part_of(GO:1901224),has_input(UniProtKB:P19838-PRO_0000030311),part_of(GO:0051092)|part_of(GO:1901224),has_input(UniProtKB:Q04206),part_of(GO:0051092)
- UniProtKB Q09472 EP300 involved_in GO:0018394 PMID:23962722 IDA P Histone acetyltransferase p300 EP300|P300 protein taxon:9606 20180125 ARUK-UCL has_input(UniProtKB:P10636-6),negatively_regulates(GO:0051259)
- UniProtKB Q09472 EP300 involved_in GO:0051092 PMID:23811396 IDA P Histone acetyltransferase p300 EP300|P300 protein taxon:9606 20201201 ARUK-UCL has_input(UniProtKB:P19838-PRO_0000030311),part_of(GO:1901224),part_of(GO:0045944)|has_input(UniProtKB:Q04206),part_of(GO:1901224),part_of(GO:0045944)
- UniProtKB Q09472 EP300 involved_in GO:1905636 PMID:23811396 IDA P Histone acetyltransferase p300 EP300|P300 protein taxon:9606 20201201 ARUK-UCL part_of(GO:1901224),part_of(GO:0051092),has_input(UniProtKB:P19838-PRO_0000030311)|part_of(GO:1901224),has_input(UniProtKB:Q04206),part_of(GO:0051092)
- UniProtKB Q12852 MAP3K12 involved_in GO:0018105 GO_REF:0000024 ISS UniProtKB:Q60700 P Mitogen-activated protein kinase kinase kinase 12 MAP3K12|ZPK protein taxon:9606 20180716 ARUK-UCL has_input(UniProtKB:P45985),occurs_in(CL:0000540)
- UniProtKB Q12852 MAP3K12 involved_in GO:0043507 GO_REF:0000024 ISS UniProtKB:Q60700 P Mitogen-activated protein kinase kinase kinase 12 MAP3K12|ZPK protein taxon:9606 20210421 ARUK-UCL has_input(UniProtKB:P45984),occurs_in(CL:0000540)|has_input(UniProtKB:P45983),occurs_in(CL:0000540)
- UniProtKB Q12852 MAP3K12 involved_in GO:0045860 GO_REF:0000024 ISS UniProtKB:Q60700 P Mitogen-activated protein kinase kinase kinase 12 MAP3K12|ZPK protein taxon:9606 20210421 ARUK-UCL has_input(UniProtKB:P45985),occurs_in(CL:0000540)
- UniProtKB Q12879 GRIN2A involved_in GO:0097202 PMID:17526495 TAS P Glutamate receptor ionotropic, NMDA 2A GRIN2A|NMDAR2A protein taxon:9606 20171218 ARUK-UCL
- UniProtKB Q13224 GRIN2B involved_in GO:2001056 PMID:17526495 ISS UniProtKB:Q00960 P Glutamate receptor ionotropic, NMDA 2B GRIN2B|NMDAR2B protein taxon:9606 20171218 ARUK-UCL occurs_in(CL:0002608)
- UniProtKB Q13464 ROCK1 involved_in GO:0010922 PMID:27221467 IMP P Rho-associated protein kinase 1 ROCK1 protein taxon:9606 20210720 ARUK-UCL has_input(UniProtKB:P60484),occurs_in(CL:0002319)
- UniProtKB Q13492 PICALM involved_in GO:0043547 PMID:26005850 IMP P Phosphatidylinositol-binding clathrin assembly protein PICALM|CALM protein taxon:9606 20190523 ARUK-UCL occurs_in(CL:1001602),has_input(UniProtKB:P20339)|occurs_in(CL:1001602),has_input(UniProtKB:Q15907)
- UniProtKB Q13526 PIN1 involved_in GO:0032092 PMID:24964035 IDA P Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 protein taxon:9606 20180516 ARUK-UCL has_input(UniProtKB:Q15796),has_input(UniProtKB:P10636)
- UniProtKB Q13547 HDAC1 involved_in GO:0052548 PMID:19057576 IMP P Histone deacetylase 1 HDAC1|RPD3L1 protein taxon:9606 20181114 ARUK-UCL has_input(UniProtKB:P08473)
- UniProtKB Q13571 LAPTM5 involved_in GO:0006919 PMID:28464033 IMP P Lysosomal-associated transmembrane protein 5 LAPTM5|KIAA0085 protein taxon:9606 20201015 ARUK-UCL
- UniProtKB Q13627 DYRK1A involved_in GO:0006468 PMID:24327345 TAS P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171204 ARUK-UCL has_input(UniProtKB:O43426)|has_input(UniProtKB:P49418)|has_input(UniProtKB:P10636)|has_input(UniProtKB:P46821)|has_input(UniProtKB:P37840)
- UniProtKB Q13627 DYRK1A involved_in GO:0006468 PMID:28377597 TAS P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171204 ARUK-UCL has_input(UniProtKB:O75533)|has_input(UniProtKB:Q96S94)|has_input(UniProtKB:Q07955)|has_input(UniProtKB:Q16629)|has_input(UniProtKB:Q01130)|has_input(UniProtKB:Q13247)
- UniProtKB Q13627 DYRK1A involved_in GO:0018105 GO_REF:0000024 ISS UniProtKB:Q63470 P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171205 ARUK-UCL has_input(UniProtKB:Q16629)
- UniProtKB Q13627 DYRK1A involved_in GO:0018105 PMID:25556849 IGI UniProtKB:Q9Y463 P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20180130 ARUK-UCL has_input(UniProtKB:P10636-8),occurs_in(CL:0000540)
- UniProtKB Q13627 DYRK1A involved_in GO:0018107 PMID:25556849 ISS UniProtKB:Q63470 P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20180130 ARUK-UCL has_input(UniProtKB:P10636-8),occurs_in(CL:0010012)
- UniProtKB Q13627 DYRK1A involved_in GO:0036289 PMID:24327345 TAS P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171204 ARUK-UCL causally_upstream_of(GO:0033674)
- UniProtKB Q13627 DYRK1A involved_in GO:0038083 PMID:24327345 IDA P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171205 ARUK-UCL occurs_in(GO:0005829)
- UniProtKB Q13627 DYRK1A involved_in GO:0038083 PMID:24327345 TAS P Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A|DYRK|MNB|MNBH protein taxon:9606 20171204 ARUK-UCL positively_regulates(GO:0016301)
- UniProtKB Q14254 FLOT2 involved_in GO:0051092 PMID:23319823 IMP P Flotillin-2 FLOT2|ESA1|M17S1 protein taxon:9606 20181203 ARUK-UCL
- UniProtKB Q14469 HES1 involved_in GO:0043433 GO_REF:0000024 ISS UniProtKB:P35428 P Transcription factor HES-1 HES1|BHLHB39|HL|HRY protein taxon:9606 20200505 ARUK-UCL
- UniProtKB Q15077 P2RY6 involved_in GO:0007202 PMID:17410128 TAS P P2Y purinoceptor 6 P2RY6|PP2891 protein taxon:9606 20180529 ARUK-UCL positively_regulates(GO:0032959),positively_regulates(GO:0051209)
- UniProtKB Q15077 P2RY6 involved_in GO:0031587 GO_REF:0000024 ISS UniProtKB:Q63371 P P2Y purinoceptor 6 P2RY6|PP2891 protein taxon:9606 20191216 ARUK-UCL part_of(GO:1905835),has_input(CHEBI:17659),occurs_in(CL:0000129)
- UniProtKB Q15077 P2RY6 involved_in GO:0031587 PMID:17410128 TAS P P2Y purinoceptor 6 P2RY6|PP2891 protein taxon:9606 20180529 ARUK-UCL
- UniProtKB Q15109 AGER involved_in GO:1902961 PMID:22406537 IGI UniProtKB:P05067-PRO_0000000093 P Advanced glycosylation end product-specific receptor AGER|RAGE protein taxon:9606 20190717 ARUK-UCL occurs_in(UBERON:0000956),has_input(UniProtKB:P56817)|occurs_in(UBERON:0002421),has_input(UniProtKB:P56817)
- UniProtKB Q15139 PRKD1 acts_upstream_of GO:0018107 GO_REF:0000024 ISS UniProtKB:Q62101 P Serine/threonine-protein kinase D1 PRKD1|PKD|PKD1|PRKCM protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:Q9UHW9)
- UniProtKB Q15555 MAPRE2 involved_in GO:0043547 PMID:25490267 ISS UniProtKB:Q8R001 P Microtubule-associated protein RP/EB family member 2 MAPRE2|RP1 protein taxon:9606 20180719 ARUK-UCL occurs_in(CL:0000312),has_input(UniProtKB:P62330)
- UniProtKB Q15569 TESK1 involved_in GO:0071901 PMID:18216281 ISS UniProtKB:Q63572 P Dual specificity testis-specific protein kinase 1 TESK1 protein taxon:9606 20171109 ARUK-UCL has_input(UniProtKB:Q7L7X3)
- UniProtKB Q15628 TRADD involved_in GO:0051092 PMID:25732226 IMP P Tumor necrosis factor receptor type 1-associated DEATH domain protein TRADD protein taxon:9606 20181101 ARUK-UCL
- UniProtKB Q15742 NAB2 involved_in GO:1902949 GO_REF:0000024 ISS UniProtKB:D4A4F4 P NGFI-A-binding protein 2 NAB2|MADER protein taxon:9606 20230301 ARUK-UCL occurs_in(CL:0010012)
- UniProtKB Q15848 ADIPOQ involved_in GO:0110113 PMID:18703020 IDA P Adiponectin ADIPOQ|ACDC|ACRP30|APM1|GBP28 protein taxon:9606 20201016 ARUK-UCL occurs_in(CL:0000235),has_output(UniProtKB:O95477)
- UniProtKB Q5T7W0 ZNF618 involved_in GO:0035563 PMID:27129234 IDA P Zinc finger protein 618 ZNF618|KIAA1952 protein taxon:9606 20200828 ARUK-UCL
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0006468 PMID:19118186 IMP P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20171102 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0018105 PMID:16923168 IDA P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20190619 ARUK-UCL has_input(UniProtKB:P10636),positively_regulates(GO:0051258)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0018105 PMID:30556160 IGI RNAcentral:URS0000565C8D_9606 P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20210720 ARUK-UCL has_input(UniProtKB:P10636),occurs_in(UBERON:0000955)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0018107 PMID:16923168 IDA P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20190619 ARUK-UCL has_input(UniProtKB:P10636),positively_regulates(GO:0051258)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0018108 PMID:16923168 IDA P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20190619 ARUK-UCL has_input(UniProtKB:P10636),positively_regulates(GO:0051258)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:0032091 PMID:19118186 IMP P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20171103 ARUK-UCL has_input(UniProtKB:Q15078),has_input(UniProtKB:P60709)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:1904031 PMID:19118186 IMP P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20171103 ARUK-UCL has_input(UniProtKB:Q00535)
- UniProtKB Q5TCY1 TTBK1 involved_in GO:2001056 PMID:19118186 IMP P Tau-tubulin kinase 1 TTBK1|BDTK|KIAA1855 protein taxon:9606 20191216 ARUK-UCL has_input(UniProtKB:P07384)
- UniProtKB Q6IQ55 TTBK2 involved_in GO:0018105 PMID:26323690 IDA P Tau-tubulin kinase 2 TTBK2|KIAA0847 protein taxon:9606 20211119 ARUK-UCL has_input(UniProtKB:O00139),negatively_regulates(GO:0007019),negatively_regulates(GO:0008017),occurs_in(GO:0005874)
- UniProtKB Q6IQ55 TTBK2 involved_in GO:1904527 PMID:26323690 IDA P Tau-tubulin kinase 2 TTBK2|KIAA0847 protein taxon:9606 20171106 ARUK-UCL has_input(UniProtKB:O00139)
- UniProtKB Q6P1M0 SLC27A4 acts_upstream_of_or_within GO:0090630 PMID:25603556 IDA P Long-chain fatty acid transport protein 4 SLC27A4|ACSVL4|FATP4 protein taxon:9606 20200923 ARUK-UCL has_input(UniProtKB:P63000)
- UniProtKB Q6ZMJ4 IL34 acts_upstream_of_or_within GO:0043406 PMID:26754294 IDA P Interleukin-34 IL34|C16orf77 protein taxon:9606 20200320 ARUK-UCL has_input(UniProtKB:P28482),occurs_in(CL:0000235)|has_input(UniProtKB:P27361),occurs_in(CL:0000235)
- UniProtKB Q6ZMJ4 IL34 acts_upstream_of_or_within GO:0061098 PMID:26754294 IDA P Interleukin-34 IL34|C16orf77 protein taxon:9606 20200320 ARUK-UCL has_input(UniProtKB:Q05397),occurs_in(CL:0000235)
- UniProtKB Q7KZI7 MARK2 involved_in GO:0018105 PMID:10542369 IDA P Serine/threonine-protein kinase MARK2 MARK2|EMK1 protein taxon:9606 20180328 ARUK-UCL has_input(UniProtKB:P11137),negatively_regulates(GO:0000226)|has_input(UniProtKB:P27816),negatively_regulates(GO:0000226)
- UniProtKB Q7KZI7 MARK2 involved_in GO:0018105 PMID:16717194 IDA P Serine/threonine-protein kinase MARK2 MARK2|EMK1 protein taxon:9606 20180508 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB Q7KZI7 MARK2 involved_in GO:0018105 PMID:16717194 ISS UniProtKB:O08679 P Serine/threonine-protein kinase MARK2 MARK2|EMK1 protein taxon:9606 20180508 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:P10636)
- UniProtKB Q7KZI7 MARK2 involved_in GO:0018105 PMID:24251416 ISS UniProtKB:O08679 P Serine/threonine-protein kinase MARK2 MARK2|EMK1 protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P10636),regulates(GO:0008017)
- UniProtKB Q7KZI7 MARK2 involved_in GO:1904526 PMID:24251416 ISS UniProtKB:O08679 P Serine/threonine-protein kinase MARK2 MARK2|EMK1 protein taxon:9606 20180515 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB Q7L7X3 TAOK1 involved_in GO:0046777 PMID:18216281 ISS UniProtKB:O88664 P Serine/threonine-protein kinase TAO1 TAOK1|KIAA1361|MAP3K16|MARKK protein taxon:9606 20171109 ARUK-UCL
- UniProtKB Q7Z699 SPRED1 involved_in GO:0006469 PMID:18216281 IDA P Sprouty-related, EVH1 domain-containing protein 1 SPRED1 protein taxon:9606 20171109 ARUK-UCL has_input(UniProtKB:Q15569)
- UniProtKB Q8IV16 GPIHBP1 involved_in GO:0051006 PMID:29899144 IDA P Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1|HBP1 protein taxon:9606 20190715 ARUK-UCL has_input(UniProtKB:P06858)
- UniProtKB Q8N2Q7 NLGN1 involved_in GO:2000310 GO_REF:0000024 ISS UniProtKB:Q62765 P Neuroligin-1 NLGN1|KIAA1070 protein taxon:9606 20170814 ARUK-UCL occurs_in(UBERON:0002421)
- UniProtKB Q8NFF2 SLC24A4 acts_upstream_of GO:0010469 GO_REF:0000024 ISS UniProtKB:Q8CGQ8 P Sodium/potassium/calcium exchanger 4 SLC24A4|NCKX4 protein taxon:9606 20210601 ARUK-UCL has_input(UniProtKB:P56450),part_of(GO:0008277),occurs_in(UBERON:0001898),occurs_in(CL:0000540)
- UniProtKB Q8NHJ6 LILRB4 involved_in GO:0061099 PMID:16493035 IMP P Leukocyte immunoglobulin-like receptor subfamily B member 4 LILRB4|ILT3|LIR5 protein taxon:9606 20200930 ARUK-UCL has_input(UniProtKB:P29350)
- UniProtKB Q8NHJ6 LILRB4 involved_in GO:0061099 PMID:9151699 IDA P Leukocyte immunoglobulin-like receptor subfamily B member 4 LILRB4|ILT3|LIR5 protein taxon:9606 20200930 ARUK-UCL has_input(UniProtKB:P29350)
- UniProtKB Q8NHJ6 LILRB4 involved_in GO:2000272 PMID:9151699 IDA P Leukocyte immunoglobulin-like receptor subfamily B member 4 LILRB4|ILT3|LIR5 protein taxon:9606 20201001 ARUK-UCL has_input(UniProtKB:P29350)
- UniProtKB Q8TDC3 BRSK1 involved_in GO:0006468 PMID:27626661 TAS P Serine/threonine-protein kinase BRSK1 BRSK1|KIAA1811|SAD1|SADB protein taxon:9606 20180516 ARUK-UCL has_input(UniProtKB:Q86UR5)
- UniProtKB Q8WW43 APH1B involved_in GO:0010950 PMID:12297508 IMP P Gamma-secretase subunit APH-1B APH1B|PSFL|UNQ688/PRO1328 protein taxon:9606 20201110 ARUK-UCL has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)
- UniProtKB Q8WW43 APH1B involved_in GO:0010950 PMID:12763021 IGI UniProtKB:P05067|UniProtKB:P49768 P Gamma-secretase subunit APH-1B APH1B|PSFL|UNQ688/PRO1328 protein taxon:9606 20201110 ARUK-UCL
- UniProtKB Q92542 NCSTN involved_in GO:0010950 PMID:12297508 IMP P Nicastrin NCSTN|KIAA0253|UNQ1874/PRO4317 protein taxon:9606 20201110 ARUK-UCL has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)
- UniProtKB Q92542 NCSTN involved_in GO:0010950 PMID:12763021 IGI UniProtKB:P05067|UniProtKB:P49768 P Nicastrin NCSTN|KIAA0253|UNQ1874/PRO4317 protein taxon:9606 20201110 ARUK-UCL
- UniProtKB Q92793 CREBBP involved_in GO:0006473 PMID:28386764 TAS P CREB-binding protein CREBBP|CBP protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB Q92796 DLG3 involved_in GO:0061098 PMID:17526495 ISS UniProtKB:Q62936 P Disks large homolog 3 DLG3|KIAA1232 protein taxon:9606 20171218 ARUK-UCL has_input(UniProtKB:Q62844)
- UniProtKB Q93084 ATP2A3 involved_in GO:0006919 PMID:16725111 IDA P Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 ATP2A3 protein taxon:9606 20191001 ARUK-UCL has_input(UniProtKB:P42574)
- UniProtKB Q93084 ATP2A3 involved_in GO:1900121 PMID:18068335 IMP P Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 ATP2A3 protein taxon:9606 20191001 ARUK-UCL occurs_in(CL:0000233),part_of(GO:0006874)
- UniProtKB Q96AC1 FERMT2 involved_in GO:0035505 PMID:29496737 IMP P Fermitin family homolog 2 FERMT2|KIND2|MIG2|PLEKHC1 protein taxon:9606 20200916 ARUK-UCL occurs_in(CL:0000134)
- UniProtKB Q96AC1 FERMT2 involved_in GO:0043547 PMID:29496737 IMP P Fermitin family homolog 2 FERMT2|KIND2|MIG2|PLEKHC1 protein taxon:9606 20200916 ARUK-UCL occurs_in(CL:0000134),has_input(UniProtKB:P61586)
- UniProtKB Q96BI3 APH1A involved_in GO:0010950 PMID:12297508 IMP P Gamma-secretase subunit APH-1A APH1A|PSF|CGI-78|UNQ579/PRO1141 protein taxon:9606 20201110 ARUK-UCL has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)
- UniProtKB Q96BI3 APH1A involved_in GO:0010950 PMID:12763021 IGI UniProtKB:P05067|UniProtKB:P49768 P Gamma-secretase subunit APH-1A APH1A|PSF|CGI-78|UNQ579/PRO1141 protein taxon:9606 20201110 ARUK-UCL
- UniProtKB Q96HZ4 HES6 involved_in GO:0043433 GO_REF:0000024 ISS UniProtKB:Q9JHE6 P Transcription cofactor HES-6 HES6|BHLHB41 protein taxon:9606 20200505 ARUK-UCL
- UniProtKB Q96SZ6 CDK5RAP1 involved_in GO:0045736 PMID:17491008 TAS P Mitochondrial tRNA methylthiotransferase CDK5RAP1 CDK5RAP1|C20orf34|CGI-05|HSPC167 protein taxon:9606 20171030 ARUK-UCL has_input(UniProtKB:Q00535)
- UniProtKB Q99490 AGAP2 involved_in GO:0061903 PMID:18374643 TAS P Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 AGAP2|CENTG1|KIAA0167 protein taxon:9606 20180307 ARUK-UCL occurs_in(UBERON:0000955)
- UniProtKB Q99538 LGMN involved_in GO:0097202 PMID:18374643 IDA P Legumain LGMN|PRSC1 protein taxon:9606 20180307 ARUK-UCL has_input(UniProtKB:Q99538)
- UniProtKB Q99538 LGMN involved_in GO:0097202 PMID:9821970 IDA P Legumain LGMN|PRSC1 protein taxon:9606 20180307 ARUK-UCL has_input(UniProtKB:Q99538)
- UniProtKB Q9BXN2 CLEC7A acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q6QLQ4 P C-type lectin domain family 7 member A CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:P05412),part_of(GO:0001878)
- UniProtKB Q9BXN2 CLEC7A acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q6QLQ4 P C-type lectin domain family 7 member A CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:Q12968),part_of(GO:0001878)
- UniProtKB Q9BXN2 CLEC7A acts_upstream_of_or_within GO:0051091 GO_REF:0000024 ISS UniProtKB:Q6QLQ4 P C-type lectin domain family 7 member A CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:Q13469),part_of(GO:0001878)
- UniProtKB Q9BXN2 CLEC7A involved_in GO:0043280 PMID:22267217 IMP P C-type lectin domain family 7 member A CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082 protein taxon:9606 20190502 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:P29466)|has_input(UniProtKB:Q14790),occurs_in(CL:0000451)
- UniProtKB Q9BXN2 CLEC7A involved_in GO:0051092 GO_REF:0000024 ISS UniProtKB:Q6QLQ4 P C-type lectin domain family 7 member A CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082 protein taxon:9606 20210416 ARUK-UCL occurs_in(CL:0000451),part_of(GO:0001878)
- UniProtKB Q9BY76 ANGPTL4 involved_in GO:0051005 PMID:29899144 IDA P Angiopoietin-related protein 4 ANGPTL4|ARP4|HFARP|PGAR|PP1158|PSEC0166|UNQ171/PRO197 protein taxon:9606 20190715 ARUK-UCL has_input(UniProtKB:P06858)
- UniProtKB Q9BYF1 ACE2 acts_upstream_of GO:2000272 PMID:18258853 IMP P Angiotensin-converting enzyme 2 ACE2|UNQ868/PRO1885 protein taxon:9606 20201016 ARUK-UCL has_input(UniProtKB:P30556)
- UniProtKB Q9BYF1 ACE2 involved_in GO:0022898 PMID:25534429 IGI UniProtKB:Q9NP91 P Angiotensin-converting enzyme 2 ACE2|UNQ868/PRO1885 protein taxon:9606 20200610 ARUK-UCL has_input(UniProtKB:Q9NP91),part_of(GO:1905737)
- UniProtKB Q9BYP7 WNK3 acts_upstream_of GO:0018107 PMID:27782176 ISS UniProtKB:Q80XP9 P Serine/threonine-protein kinase WNK3 WNK3|KIAA1566|PRKWNK3 protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:Q9UHW9),causally_upstream_of(GO:1904062)
- UniProtKB Q9BZC7 ABCA2 acts_upstream_of GO:1905598 PMID:21810484 IDA P ATP-binding cassette sub-family A member 2 ABCA2|ABC2|KIAA1062 protein taxon:9606 20190726 ARUK-UCL occurs_in(CL:0000540)
- UniProtKB Q9H1K1 ISCU involved_in GO:1904234 PMID:20436681 IMP P Iron-sulfur cluster assembly enzyme ISCU ISCU|NIFUN protein taxon:9606 20190314 ARUK-UCL
- UniProtKB Q9H244 P2RY12 involved_in GO:0007202 PMID:20091784 TAS P P2Y purinoceptor 12 P2RY12|HORK3 protein taxon:9606 20180521 ARUK-UCL part_of(GO:0071318),positively_regulates(GO:1904124)
- UniProtKB Q9H244 P2RY12 involved_in GO:0043552 PMID:20091784 TAS P P2Y purinoceptor 12 P2RY12|HORK3 protein taxon:9606 20180521 ARUK-UCL part_of(GO:0071318),positively_regulates(GO:1904124)
- UniProtKB Q9H257 CARD9 involved_in GO:0043280 PMID:22267217 IMP P Caspase recruitment domain-containing protein 9 CARD9 protein taxon:9606 20190502 ARUK-UCL has_input(UniProtKB:Q14790),occurs_in(CL:0000451)
- UniProtKB Q9H4A3 WNK1 acts_upstream_of GO:0018107 PMID:27782176 ISS UniProtKB:P83741 P Serine/threonine-protein kinase WNK1 WNK1|HSN2|KDP|KIAA0344|PRKWNK1 protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:Q9UHW9)
- UniProtKB Q9H4A3 WNK1 acts_upstream_of_or_within GO:0018107 PMID:27782176 IMP P Serine/threonine-protein kinase WNK1 WNK1|HSN2|KDP|KIAA0344|PRKWNK1 protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:O95747)
- UniProtKB Q9H4A3 WNK1 acts_upstream_of_or_within GO:0018107 PMID:27782176 IMP P Serine/threonine-protein kinase WNK1 WNK1|HSN2|KDP|KIAA0344|PRKWNK1 protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:P55011)
- UniProtKB Q9H4A3 WNK1 acts_upstream_of_or_within GO:0018107 PMID:27782176 IMP P Serine/threonine-protein kinase WNK1 WNK1|HSN2|KDP|KIAA0344|PRKWNK1 protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:Q9UEW8)
- UniProtKB Q9HBJ8 CLTRN involved_in GO:0022898 PMID:25534429 IGI UniProtKB:Q9NP91 P Collectrin CLTRN|TMEM27|UNQ679/PRO1312 protein taxon:9606 20200610 ARUK-UCL has_input(UniProtKB:Q9NP91),part_of(GO:1905737)
- UniProtKB Q9NPH5 NOX4 involved_in GO:0061098 PMID:27525436 ISS UniProtKB:Q9JHI8 P NADPH oxidase 4 NOX4|RENOX protein taxon:9606 20230605 ARUK-UCL occurs_in(CL:0000746),has_input(UniProtKB:P06241),part_of(GO:0006979)
- UniProtKB Q9NPP4 NLRC4 involved_in GO:0097202 PMID:15882992 IGI UniProtKB:P10749,UniProtKB:P29466 P NLR family CARD domain-containing protein 4 NLRC4|CARD12|CLAN|CLAN1|IPAF|UNQ6189/PRO20215 protein taxon:9606 20200319 ARUK-UCL part_of(GO:0032731),has_input(UniProtKB:P29466),part_of(GO:0010954)
- UniProtKB Q9NRI5 DISC1 involved_in GO:0032091 GO_REF:0000024 ISS UniProtKB:Q811T9 P Disrupted in schizophrenia 1 protein DISC1|KIAA0457 protein taxon:9606 20170814 ARUK-UCL has_input(UniProtKB:P97924),has_input(UniProtKB:Q99K10)
- UniProtKB Q9NRW4 DUSP22 involved_in GO:0035335 PMID:20018849 IDA P Dual specificity protein phosphatase 22 DUSP22|JSP1|LMWDSP2|MKPX protein taxon:9606 20180716 ARUK-UCL has_input(UniProtKB:Q05397)
- UniProtKB Q9NRW4 DUSP22 involved_in GO:1903996 PMID:20018849 IMP P Dual specificity protein phosphatase 22 DUSP22|JSP1|LMWDSP2|MKPX protein taxon:9606 20180719 ARUK-UCL has_input(UniProtKB:Q05397)
- UniProtKB Q9NZ42 PSENEN involved_in GO:0010950 PMID:12522139 IMP P Gamma-secretase subunit PEN-2 PSENEN|PEN2|MDS033 protein taxon:9606 20201110 ARUK-UCL has_input(UniProtKB:P49768)
- UniProtKB Q9NZ42 PSENEN involved_in GO:0010950 PMID:12763021 IGI UniProtKB:P05067|UniProtKB:P49768 P Gamma-secretase subunit PEN-2 PSENEN|PEN2|MDS033 protein taxon:9606 20201110 ARUK-UCL
- UniProtKB Q9NZC2 TREM2 involved_in GO:0033674 PMID:31902528 IDA P Triggering receptor expressed on myeloid cells 2 TREM2 protein taxon:9606 20210301 ARUK-UCL has_input(UniProtKB:P43405)
- UniProtKB Q9NZC2 TREM2 involved_in GO:1901980 PMID:29518356 ISS UniProtKB:Q99NH8 P Triggering receptor expressed on myeloid cells 2 TREM2 protein taxon:9606 20181212 ARUK-UCL occurs_in(CL:0000129)
- UniProtKB Q9P0L2 MARK1 involved_in GO:0018105 PMID:10542369 NAS P Serine/threonine-protein kinase MARK1 MARK1|KIAA1477|MARK protein taxon:9606 20180328 ARUK-UCL has_input(UniProtKB:P11137),regulates(GO:0000226)|has_input(UniProtKB:P27816),regulates(GO:0000226)
- UniProtKB Q9UBN7 HDAC6 involved_in GO:0006476 PMID:28386764 TAS P Histone deacetylase 6 HDAC6|KIAA0901|JM21 protein taxon:9606 20180122 ARUK-UCL has_input(UniProtKB:P10636)
- UniProtKB Q9UBN7 HDAC6 involved_in GO:0034983 PMID:23962722 IMP P Histone deacetylase 6 HDAC6|KIAA0901|JM21 protein taxon:9606 20180126 ARUK-UCL has_input(UniProtKB:P10636-6),positively_regulates(GO:0051259),positively_regulates(GO:0018105)
- UniProtKB Q9UBN7 HDAC6 involved_in GO:0090042 PMID:28386764 TAS P Histone deacetylase 6 HDAC6|KIAA0901|JM21 protein taxon:9606 20180122 ARUK-UCL
- UniProtKB Q9UDY8 MALT1 involved_in GO:0043280 PMID:22267217 IMP P Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT1|MLT protein taxon:9606 20190502 ARUK-UCL has_input(UniProtKB:Q14790),occurs_in(CL:0000451)
- UniProtKB Q9UEW8 STK39 involved_in GO:0018107 GO_REF:0000024 ISS UniProtKB:Q9Z1W9 P STE20/SPS1-related proline-alanine-rich protein kinase STK39|PASK|SPAK protein taxon:9606 20200119 ARUK-UCL has_input(UniProtKB:Q924N4)
- UniProtKB Q9UIG8 SLCO3A1 involved_in GO:0051092 PMID:24945726 IMP P Solute carrier organic anion transporter family member 3A1 SLCO3A1|OATP3A1|OATPD|SLC21A11 protein taxon:9606 20191127 ARUK-UCL occurs_in(CL:0002518)
- UniProtKB Q9UKV0 HDAC9 involved_in GO:0051005 PMID:28855441 IDA P Histone deacetylase 9 HDAC9|HDAC7|HDAC7B|HDRP|KIAA0744|MITR protein taxon:9606 20181203 ARUK-UCL occurs_in(CL:0000235)
- UniProtKB Q9UL54 TAOK2 involved_in GO:0032147 PMID:22683681 TAS P Serine/threonine-protein kinase TAO2 TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431 protein taxon:9606 20171117 ARUK-UCL has_input(UniProtKB:Q9UL54)
- UniProtKB Q9UL54 TAOK2 involved_in GO:0046777 PMID:22683681 TAS P Serine/threonine-protein kinase TAO2 TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431 protein taxon:9606 20171117 ARUK-UCL part_of(GO:0032147)
- UniProtKB Q9ULZ3 PYCARD involved_in GO:0043280 PMID:22267217 IMP P Apoptosis-associated speck-like protein containing a CARD PYCARD|ASC|CARD5|TMS1 protein taxon:9606 20190502 ARUK-UCL occurs_in(CL:0000451),has_input(UniProtKB:Q14790)
- UniProtKB Q9UPR5 SLC8A2 acts_upstream_of_or_within GO:0071902 GO_REF:0000024 ISS UniProtKB:Q8K596 P Sodium/calcium exchanger 2 SLC8A2|KIAA1087|NCX2 protein taxon:9606 20191210 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)
- UniProtKB Q9UPY8 MAPRE3 involved_in GO:0045860 PMID:26323690 IDA P Microtubule-associated protein RP/EB family member 3 MAPRE3 protein taxon:9606 20171106 ARUK-UCL has_input(UniProtKB:Q6IQ55)
- UniProtKB Q9Y2C9 TLR6 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:O00206,UniProtKB:P05067-PRO_0000000092,UniProtKB:P16671 P Toll-like receptor 6 TLR6 protein taxon:9606 20170517 ARUK-UCL
- UniProtKB Q9Y2C9 TLR6 involved_in GO:0051092 PMID:20037584 IGI UniProtKB:O00206,UniProtKB:P16671 P Toll-like receptor 6 TLR6 protein taxon:9606 20170517 ARUK-UCL occurs_in(CL:0000235),positively_regulates(GO:0002269),part_of(GO:0071404)
- UniProtKB Q9Y6K5 OAS3 involved_in GO:0060700 PMID:25275129 IDA P 2'-5'-oligoadenylate synthase 3 OAS3|P/OKcl.4 protein taxon:9606 20210215 ARUK-UCL part_of(GO:0051607)
- ComplexPortal CPX-1062 abeta-40-42_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 40/42 complex beta-amyloid protein 40/42 heterodimer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterodimer|amyloid-beta-40/42 heterodimer|amyloid beta protein 40/42 heterodimer|beta-amyloid-40/42 heterodimer|beta amyloid protein 40/42 heterodimer|Abeta protein 40/42 complex|APP dimer protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1069 abeta-40_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 40 complex beta-amyloid protein 40 homodimer|beta-amyloid protein 40 complex|beta-amyloid-40 complex|beta amyloid protein 40 complex|amyloid-beta-40 complex|amyloid beta protein 40 complex|amyloid-beta protein 40 homodimer|amyloid-beta-40 homodimer|amyloid beta protein 40 homodimer|beta-amyloid-40 homodimer|beta amyloid protein 40 homodimer|APP dimer|Abeta protein 40 complex protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1070 abeta-42_human involved_in GO:0071902 PMID:20395454 IGI UniProtKB:P07550 P Amyloid-beta protein 42 complex beta-amyloid protein 42 homodimer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 homodimer|amyloid-beta-42 homodimer|amyloid beta protein 42 homodimer|beta-amyloid-42 homodimer|beta amyloid protein 42 homodimer|APP dimer|Abeta protein 42 complex protein_complex taxon:9606 20170525 ARUK-UCL part_of(GO:0010739),has_input(UniProtKB:P42261),positively_regulates(GO:0004971)
- ComplexPortal CPX-1070 abeta-42_human involved_in GO:1904426 PMID:20395454 IGI UniProtKB:P07550 P Amyloid-beta protein 42 complex beta-amyloid protein 42 homodimer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 homodimer|amyloid-beta-42 homodimer|amyloid beta protein 42 homodimer|beta-amyloid-42 homodimer|beta amyloid protein 42 homodimer|APP dimer|Abeta protein 42 complex protein_complex taxon:9606 20200724 ARUK-UCL
- ComplexPortal CPX-1070 abeta-42_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 42 complex beta-amyloid protein 42 homodimer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 homodimer|amyloid-beta-42 homodimer|amyloid beta protein 42 homodimer|beta-amyloid-42 homodimer|beta amyloid protein 42 homodimer|APP dimer|Abeta protein 42 complex protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1070 abeta-42_human involved_in GO:2000969 PMID:20395454 IGI UniProtKB:P07550 P Amyloid-beta protein 42 complex beta-amyloid protein 42 homodimer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 homodimer|amyloid-beta-42 homodimer|amyloid beta protein 42 homodimer|beta-amyloid-42 homodimer|beta amyloid protein 42 homodimer|APP dimer|Abeta protein 42 complex protein_complex taxon:9606 20170525 ARUK-UCL part_of(GO:0010739),has_input(UniProtKB:P42261)
- ComplexPortal CPX-1120 abeta-40-42-oligomer_human involved_in GO:0032092 PMID:29518356 IDA P Amyloid-beta protein 40/42 oligomeric complex fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer protein_complex taxon:9606 20181212 ARUK-UCL occurs_in(CL:0000129),regulates_o_occurs_in(CL:0000129),has_input(UniProtKB:O43914),has_input(UniProtKB:Q9NZC2)
- ComplexPortal CPX-1120 abeta-40-42-oligomer_human involved_in GO:1903609 PMID:29518356 IDA P Amyloid-beta protein 40/42 oligomeric complex fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer protein_complex taxon:9606 20181212 ARUK-UCL occurs_in(CL:0000129),regulates_o_occurs_in(CL:0000129)
- ComplexPortal CPX-1120 abeta-40-42-oligomer_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 40/42 oligomeric complex fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0032092 PMID:24658113 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL occurs_in(CL:0002608),has_input(UniProtKB:P54764),has_input(UniProtKB:P00519)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0032147 PMID:23386614 IGI UniProtKB:P04925 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20210428 ARUK-UCL has_input(UniProtKB:P06241),occurs_in(GO:0045121)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0043085 PMID:23386614 IGI UniProtKB:P04925 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170626 ARUK-UCL has_input(UniProtKB:P56817),positively_regulates(GO:0034205)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0043507 PMID:23164821 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0044092 PMID:23386614 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170626 ARUK-UCL has_input(UniProtKB:P04156),positively_regulates(GO:0034205)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0051091 PMID:23921129 IGI UniProtKB:P05067 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170622 ARUK-UCL regulates_o_occurs_in(CL:0002609),part_of(GO:1904646),has_input(UniProtKB:P05412)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061098 PMID:15190117 IGI UniProtKB:P05067:PRO_0000000092 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170614 ARUK-UCL occurs_in(UBERON:0002421),part_of(GO:0045666)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061098 PMID:24012003 IGI UniProtKB:P04156,UniProtKB:P41594 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL has_input(UniProtKB:P06241),occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061098 PMID:24658113 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),regulates_o_occurs_in(GO:0043025)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),regulates_o_occurs_in(GO:0005634),regulates_o_occurs_in(CL:0000540)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),regulates_o_occurs_in(GO:0030425)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061098 PMID:24658113 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL has_input(UniProtKB:P54764),occurs_in(UBERON:0002421),regulates_o_occurs_in(CL:0002608)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061098 PMID:24658113 IGI UniProtKB:Q03137 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002608),has_input(UniProtKB:P00520)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0061907 PMID:20739563 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170703 ARUK-UCL regulates_o_occurs_in(UBERON:0022337),regulates_o_occurs_in(UBERON:0022327)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0097202 PMID:23386614 TAS P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170626 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0150072 PMID:28912710 IC GO:0010628 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20190909 ARUK-UCL regulates_o_occurs_in(CL:0000129),part_of(GO:0001774),has_input(UniProtKB:P05089)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1902938 PMID:24012003 IGI UniProtKB:P04156,UniProtKB:P41594 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1902949 PMID:23164821 IGI UniProtKB:A0A0H2UHR3 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1902949 PMID:23164821 IGI UniProtKB:D4A4F4 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1903048 PMID:19118188 IGI UniProtKB:P05067:PRO_0000000092,UniProtKB:P49582 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20180223 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:P49582),part_of(GO:1900273)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1904685 PMID:28912710 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20190909 ARUK-UCL happens_during(UBERON:0007222),has_input(UniProtKB:P08253),regulates_o_occurs_in(CL:0000129)|has_input(UniProtKB:P14780),regulates_o_occurs_in(CL:0000129)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1180 abeta-40-oligomer_human involved_in GO:2000310 PMID:26224839 TAS P Amyloid-beta protein 40 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40 homooligomer|beta-amyloid protein 40 complex|beta-amyloid-40 complex|beta amyloid protein 40 complex|amyloid-beta-40 complex|amyloid beta protein 40 complex|amyloid-beta protein 40 homooligomer|amyloid-beta-40 homooligomer|amyloid beta protein 40 homooligomer|beta-amyloid-40 heterooligomer|beta amyloid protein 40 homooligomer|Abeta protein 40 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170831 ARUK-UCL causally_upstream_of(GO:1905809)
- ComplexPortal CPX-1826 intg_am_b2_human involved_in GO:2000363 GO_REF:0000024 ISS ComplexPortal:CPX-3129 P Integrin alphaM-beta2 complex alphambeta2 integrin complex|alpha-M/beta-2 integrin complex|ITGAM:ITGB2|Integrin MAC-1|CR3|Complement receptor 3|Macrophage 1 antigen|CD11b/CD18 protein_complex taxon:9606 20170710 ARUK-UCL occurs_in(UBERON:0001891),regulates_o_occurs_in(CL:0000243),occurs_in(CL:0000243),has_output(CHEBI:15551),part_of(GO:0033554)|occurs_in(UBERON:0001891),regulates_o_occurs_in(CL:0000243),occurs_in(CL:0000540),has_output(CHEBI:15551),part_of(GO:0033554)
- UniProtKB P01138 NGF involved_in GO:0006919 PMID:11927634 IGI UniProtKB:P08138 P Beta-nerve growth factor NGF|NGFB protein taxon:9606 20170906 ARUK-UCL positively_regulates(GO:0051402) UniProtKB:P01138-PRO_0000019600
- UniProtKB P05067 APP involved_in GO:0032092 PMID:26005850 IDA P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170522 ARUK-UCL has_input(UniProtKB:O95782),has_input(UniProtKB:Q07954),occurs_in(UBERON:0013694)|has_input(UniProtKB:Q00610),has_input(UniProtKB:Q07954),occurs_in(UBERON:0013694)|has_input(UniProtKB:Q13492),has_input(UniProtKB:Q07954),occurs_in(UBERON:0013694) UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP involved_in GO:0043280 PMID:21803450 IDA P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170201 ARUK-UCL part_of(GO:1905893)|part_of(GO:1905896)|part_of(GO:1905898) UniProtKB:P05067-PRO_0000000099
- UniProtKB P05067 APP involved_in GO:0043406 GO_REF:0000024 ISS UniProtKB:P08592-PRO_0000000163 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20210421 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:P28482) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0043406 GO_REF:0000024 ISS UniProtKB:P08592-PRO_0000000163 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20220316 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:P28482),activated_by(CHEBI:39124) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0043406 PMID:11404397 TAS P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20210421 ARUK-UCL occurs_in(CL:0010012)|occurs_in(CL:0002608) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0051092 PMID:20037584 IGI UniProtKB:O00206,UniProtKB:P16671,UniProtKB:Q9Y2C9 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170517 ARUK-UCL UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0061098 PMID:15190117 IGI ComplexPortal:CPX-1134 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20210421 ARUK-UCL occurs_in(UBERON:0002421),part_of(GO:0045666) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:1900122 PMID:20037584 IDA P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170517 ARUK-UCL has_input(UniProtKB:O00206),has_input(UniProtKB:P16671),has_input(UniProtKB:Q9Y2C9),occurs_in(CL:0000576) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:1900122 PMID:20141570 IDA P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170531 ARUK-UCL occurs_in(CL:0000127),occurs_in(GO:0016020),has_input(UniProtKB:F1M670),has_input(UniProtKB:M0R9F7)|occurs_in(CL:0000129),occurs_in(GO:0016020),has_input(UniProtKB:F1M670),has_input(UniProtKB:M0R9F7) UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:1902949 PMID:23164821 IGI UniProtKB:D4A4F4 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230301 ARUK-UCL occurs_in(CL:0010012) UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP involved_in GO:1902961 PMID:22406537 IGI UniProtKB:Q15109 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20190717 ARUK-UCL occurs_in(UBERON:0000956),has_input(UniProtKB:P56817)|occurs_in(UBERON:0002421),has_input(UniProtKB:P56817) UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP involved_in GO:1903048 PMID:19118188 IGI ComplexPortal:CPX-1134,UniProtKB:P49582 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20180223 ARUK-UCL occurs_in(UBERON:0002421),has_input(UniProtKB:P49582),part_of(GO:1900273) UniProtKB:P05067-PRO_0000000092
- UniProtKB P10997 IAPP NOT|involved_in GO:1900019 PMID:22500019 NAS P Islet amyloid polypeptide IAPP protein taxon:9606 20170524 ARUK-UCL UniProtKB:P10997-PRO_0000004106
- UniProtKB P24001 IL32 acts_upstream_of GO:1905636 PMID:23729669 IDA P Interleukin-32 IL32|NK4|TAIF protein taxon:9606 20211118 ARUK-UCL has_input(UniProtKB:Q04206) UniProtKB:P24001-1
- UniProtKB P58400 NRXN1 involved_in GO:1900020 PMID:26078884 IDA P Neurexin-1-beta NRXN1 protein taxon:9606 20170814 ARUK-UCL has_input(UniProtKB:Q05586),occurs_in(CL:0010012) UniProtKB:P58400
- UniProtKB Q15078 CDK5R1 involved_in GO:2000273 PMID:29020624 IDA P Cyclin-dependent kinase 5 activator 1 CDK5R1|CDK5R|NCK5A protein taxon:9606 20201016 ARUK-UCL occurs_in(CL:0000129),has_input(UniProtKB:P25942) UniProtKB:Q15078-PRO_0000004795
- UniProtKB Q15078 CDK5R1 involved_in GO:2000273 PMID:29020624 IDA P Cyclin-dependent kinase 5 activator 1 CDK5R1|CDK5R|NCK5A protein taxon:9606 20201016 ARUK-UCL occurs_in(CL:0000129),has_input(UniProtKB:Q07108) UniProtKB:Q15078-PRO_0000004795
- RNAcentral URS000003FD55_9606 URS000003FD55_9606 involved_in GO:0010951 PMID:24352696 IDA P Homo sapiens (human) hsa-miR-339-5p miRNA taxon:9606 20200720 ARUK-UCL has_input(UniProtKB:P56817),causally_upstream_of(GO:1902430)
- RNAcentral URS000005A8ED_9606 URS000005A8ED_9606 involved_in GO:0032410 PMID:28411377 IMP P Homo sapiens (human) hsa-miR-495-3p miRNA taxon:9606 20210518 ARUK-UCL has_input(UniProtKB:P08183),causally_upstream_of(GO:1905700)
- RNAcentral URS00000A33DB_9606 URS00000A33DB_9606 acts_upstream_of GO:1905124 PMID:25584808 IGI UniProtKB:P04062 P Homo sapiens (human) hsa-miR-127-5p miRNA taxon:9606 20210727 ARUK-UCL occurs_in(CL:0000057)
- RNAcentral URS00000A939F_9606 URS00000A939F_9606 involved_in GO:0032410 PMID:25714665 IDA P Homo sapiens (human) hsa-miR-326 miRNA taxon:9606 20211104 ARUK-UCL has_input(UniProtKB:P33527),causally_upstream_of(GO:1905700)
- RNAcentral URS0000183BED_9606 URS0000183BED_9606 acts_upstream_of_or_within GO:2000272 PMID:29901200 IDA P Homo sapiens (human) hsa-miR-23b-3p miRNA taxon:9606 20201016 ARUK-UCL has_input(UniProtKB:Q14626)
- RNAcentral URS00001CC379_9606 URS00001CC379_9606 involved_in GO:0051006 PMID:28855441 IDA P Homo sapiens (human) hsa-miR-182-5p miRNA taxon:9606 20181203 ARUK-UCL occurs_in(CL:0000235)
- RNAcentral URS00001CC379_9606 URS00001CC379_9606 involved_in GO:1901726 PMID:28855441 IDA P Homo sapiens (human) hsa-miR-182-5p miRNA taxon:9606 20181203 ARUK-UCL occurs_in(CL:0000235)
- RNAcentral URS00001D6BAE_9606 URS00001D6BAE_9606 involved_in GO:0051001 PMID:28089352 IDA P Homo sapiens (human) hsa-miR-212-3p miRNA taxon:9606 20181218 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:P29475)
- RNAcentral URS00001DC04F_9606 URS00001DC04F_9606 acts_upstream_of GO:0032410 PMID:28042875 IDA P Homo sapiens (human) hsa-miR-1-3p miRNA taxon:9606 20210319 ARUK-UCL has_input(UniProtKB:P08183),part_of(GO:1905700)
- RNAcentral URS000021202F_9606 URS000021202F_9606 acts_upstream_of GO:0032410 PMID:23893241 IGI UniProtKB:P08183 P Homo sapiens (human) hsa-miR-508-5p miRNA taxon:9606 20210210 ARUK-UCL has_input(UniProtKB:P08183),part_of(GO:1905700)
- RNAcentral URS000026261D_9606 URS000026261D_9606 acts_upstream_of GO:0032088 PMID:30233718 IMP P Homo sapiens (human) hsa-miR-140-5p miRNA taxon:9606 20201102 ARUK-UCL
- RNAcentral URS000028C188_9606 URS000028C188_9606 acts_upstream_of GO:0051092 PMID:28159925 IGI UniProtKB:Q04206 P Homo sapiens (human) hsa-miR-1246 miRNA taxon:9606 20210716 ARUK-UCL occurs_in(CL:0000134),part_of(GO:1903265)
- RNAcentral URS00002DABEA_9606 URS00002DABEA_9606 involved_in GO:1902949 PMID:28947385 IDA P Homo sapiens (human) hsa-miR-125b-1-3p miRNA taxon:9606 20181217 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:Q00535)
- RNAcentral URS00002E857A_9606 URS00002E857A_9606 acts_upstream_of GO:0032410 PMID:18645025 IMP P Homo sapiens (human) hsa-miR-451a miRNA taxon:9606 20210215 ARUK-UCL part_of(GO:1905700),has_input(UniProtKB:P08183)
- RNAcentral URS000030BD69_9606 URS000030BD69_9606 acts_upstream_of GO:0071901 PMID:26330104 IMP P Homo sapiens (human) hsa-miR-34a-5p miRNA taxon:9606 20200821 ARUK-UCL has_input(UniProtKB:Q13131),part_of(GO:1902532),occurs_in(CL:0000182)
- RNAcentral URS0000316FA5_9606 URS0000316FA5_9606 involved_in GO:0071902 PMID:24027266 ISS RNAcentral:URS0000316FA5_10116 P Homo sapiens (human) hsa-miR-26b-5p miRNA taxon:9606 20190307 ARUK-UCL occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)|occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P06400)
- RNAcentral URS0000316FA5_9606 URS0000316FA5_9606 involved_in GO:1902949 PMID:24027266 ISS RNAcentral:URS0000316FA5_10116 P Homo sapiens (human) hsa-miR-26b-5p miRNA taxon:9606 20190307 ARUK-UCL occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)
- RNAcentral URS000032BD73_9606 URS000032BD73_9606 involved_in GO:0032410 PMID:28881788 IDA P Homo sapiens (human) hsa-miR-133b miRNA taxon:9606 20211104 ARUK-UCL has_input(UniProtKB:P33527),causally_upstream_of(GO:1905700)
- RNAcentral URS0000330617_9606 URS0000330617_9606 acts_upstream_of_or_within GO:0043280 PMID:31124343 IGI UniProtKB:P01375 P Homo sapiens (human) hsa-miR-27b-5p miRNA taxon:9606 20200210 ARUK-UCL occurs_in(CL:0000214),part_of(GO:2001244)
- RNAcentral URS00003496BE_9606 URS00003496BE_9606 acts_upstream_of GO:0032410 PMID:28260112 IGI UniProtKB:P08183 P Homo sapiens (human) hsa-miR-9-3p miRNA taxon:9606 20210319 ARUK-UCL has_input(UniProtKB:P08183),part_of(GO:1905700)
- RNAcentral URS00003B95DA_9606 URS00003B95DA_9606 involved_in GO:1900131 PMID:24608080 IDA P Homo sapiens (human) hsa-miR-27a-3p misc_RNA taxon:9606 20190116 ARUK-UCL occurs_in(CL:0000517)
- RNAcentral URS00003B95DA_9606 URS00003B95DA_9606 involved_in GO:1905919 PMID:24608080 IDA P Homo sapiens (human) hsa-miR-27a-3p misc_RNA taxon:9606 20220217 ARUK-UCL occurs_in(CL:0000517),has_input(UniProtKB:P35610)
- RNAcentral URS00003D1AE3_9606 URS00003D1AE3_9606 involved_in GO:0032088 PMID:30365148 IDA P Homo sapiens (human) hsa-miR-15a-5p miRNA taxon:9606 20181108 ARUK-UCL occurs_in(CL:0002585),part_of(GO:0071333)
- RNAcentral URS00003D1AE3_9606 URS00003D1AE3_9606 involved_in GO:0045736 PMID:27343180 IDA P Homo sapiens (human) hsa-miR-15a-5p miRNA taxon:9606 20181219 ARUK-UCL has_input(UniProtKB:Q00535),occurs_in(CL:0000540)
- RNAcentral URS000040780F_9606 URS000040780F_9606 involved_in GO:0032088 PMID:23319823 IDA P Homo sapiens (human) hsa-miR-138-5p miRNA taxon:9606 20181203 ARUK-UCL
- RNAcentral URS000040DCFF_9606 URS000040DCFF_9606 acts_upstream_of GO:0032410 PMID:26626440 IMP P Homo sapiens (human) hsa-miR-186-5p miRNA taxon:9606 20210210 ARUK-UCL has_input(UniProtKB:P08183),part_of(GO:1905700)
- RNAcentral URS00004176D4_9606 URS00004176D4_9606 involved_in GO:0032410 PMID:27906433 IMP P Homo sapiens (human) hsa-miR-185-5p miRNA taxon:9606 20211104 ARUK-UCL has_input(UniProtKB:P33527),causally_upstream_of(GO:1905700)
- RNAcentral URS00004176D4_9606 URS00004176D4_9606 involved_in GO:1904604 PMID:26316588 NAS P Homo sapiens (human) hsa-miR-185-5p miRNA taxon:9606 20210727 ARUK-UCL has_input(UniProtKB:Q15109)
- RNAcentral URS0000424278_9606 URS0000424278_9606 involved_in GO:1903996 PMID:29384235 IC GO:0010629 P Homo sapiens (human) Hsa-Mir-147-v1_3p (mature (guide)) miRNA taxon:9606 20190220 ARUK-UCL occurs_in(CL:0000047),has_input(UniProtKB:O60674),part_of(GO:2000736)
- RNAcentral URS0000432971_9606 URS0000432971_9606 acts_upstream_of GO:0032410 PMID:26924291 IMP P Homo sapiens (human) hsa-miR-34b-5p miRNA taxon:9606 20210215 ARUK-UCL part_of(GO:1905700),has_input(UniProtKB:P08183)
- RNAcentral URS0000476BE1_9606 URS0000476BE1_9606 involved_in GO:0045736 PMID:27343180 IDA P Homo sapiens (human) hsa-miR-103a-3p miRNA taxon:9606 20181219 ARUK-UCL has_input(UniProtKB:Q00535),occurs_in(CL:0000540)
- RNAcentral URS00004996E9_9606 URS00004996E9_9606 acts_upstream_of GO:0032410 PMID:26850595 IGI UniProtKB:P08183 P Homo sapiens (human) hsa-miR-873-5p miRNA taxon:9606 20210319 ARUK-UCL has_input(UniProtKB:P08183),part_of(GO:1905700)
- RNAcentral URS00004BCD9C_9606 URS00004BCD9C_9606 acts_upstream_of_or_within GO:1905125 PMID:25584808 IGI UniProtKB:P04062 P Homo sapiens (human) hsa-miR-16-5p miRNA taxon:9606 20210727 ARUK-UCL occurs_in(CL:0000057)
- RNAcentral URS00004BCD9C_9606 URS00004BCD9C_9606 involved_in GO:0032088 PMID:30365148 IDA P Homo sapiens (human) hsa-miR-16-5p miRNA taxon:9606 20181108 ARUK-UCL occurs_in(CL:0002585),part_of(GO:0071333)
- RNAcentral URS00004C9052_9606 URS00004C9052_9606 involved_in GO:0032410 PMID:25714665 IDA P Homo sapiens (human) hsa-miR-133a-3p miRNA taxon:9606 20211104 ARUK-UCL has_input(UniProtKB:P33527),causally_upstream_of(GO:1905700)
- RNAcentral URS00004E5112_9606 URS00004E5112_9606 acts_upstream_of GO:1901670 PMID:31574452 IDA P Homo sapiens (human) hsa-miR-675-5p miRNA taxon:9606 20200821 ARUK-UCL occurs_in(CL:0000182)
- RNAcentral URS0000527228_9606 URS0000527228_9606 involved_in GO:0032088 PMID:25732226 IDA P Homo sapiens (human) hsa-miR-30c-2-3p miRNA taxon:9606 20181101 ARUK-UCL part_of(GO:0071356)
- RNAcentral URS000055128B_9606 URS000055128B_9606 involved_in GO:1904233 PMID:20436681 IDA P Homo sapiens (human) hsa-miR-210-3p miRNA taxon:9606 20190314 ARUK-UCL
- RNAcentral URS0000565C8D_9606 URS0000565C8D_9606 involved_in GO:1902948 PMID:30556160 IDA P Homo sapiens (human) hsa-miR-219a-5p miRNA taxon:9606 20210720 ARUK-UCL has_input(UniProtKB:Q5TCY1),occurs_in(UBERON:0000955),causally_upstream_of(GO:0033137)|has_input(UniProtKB:P49841),occurs_in(UBERON:0000955),causally_upstream_of(GO:0033137)
- RNAcentral URS000059311D_9606 URS000059311D_9606 acts_upstream_of GO:0051001 PMID:25795136 ISS RNAcentral:URS000059311D_10116 P Homo sapiens (human) hsa-miR-27b-3p miRNA taxon:9606 20200813 ARUK-UCL has_input(UniProtKB:P29474),occurs_in(UBERON:0002048)
- RNAcentral URS000059311D_9606 URS000059311D_9606 involved_in GO:1900131 PMID:24608080 IDA P Homo sapiens (human) hsa-miR-27b-3p miRNA taxon:9606 20190116 ARUK-UCL occurs_in(CL:0000517)
- RNAcentral URS000059311D_9606 URS000059311D_9606 involved_in GO:1905919 PMID:24608080 IDA P Homo sapiens (human) hsa-miR-27b-3p miRNA taxon:9606 20220217 ARUK-UCL occurs_in(CL:0000517),has_input(UniProtKB:P35610)
- RNAcentral URS00005B3525_9606 URS00005B3525_9606 acts_upstream_of_or_within GO:1905125 PMID:25584808 IGI UniProtKB:P04062 P Homo sapiens (human) hsa-miR-195-5p miRNA taxon:9606 20210727 ARUK-UCL occurs_in(CL:0000057)
- RNAcentral URS00006054DA_9606 URS00006054DA_9606 involved_in GO:0051001 PMID:28089352 IDA P Homo sapiens (human) hsa-miR-132-3p miRNA taxon:9606 20181218 ARUK-UCL occurs_in(CL:0000540),has_input(UniProtKB:P29475)
- RNAcentral URS000075A42A_9606 URS000075A42A_9606 involved_in GO:0043433 PMID:27573859 IDA P Homo sapiens (human) hsa-miR-892b miRNA taxon:9606 20181115 ARUK-UCL has_input(UniProtKB:P08047)
- RNAcentral URS000075A42A_9606 URS000075A42A_9606 involved_in GO:1904684 PMID:27573859 IDA P Homo sapiens (human) hsa-miR-892b miRNA taxon:9606 20181115 ARUK-UCL has_input(UniProtKB:P14780)
- RNAcentral URS0000812128_9606 URS0000812128_9606 acts_upstream_of GO:1901670 PMID:31574452 IMP P Homo sapiens (human) H19 imprinted maternally expressed transcript lncRNA taxon:9606 20200821 ARUK-UCL occurs_in(CL:0000182)
gorule-0000020
Violates GORULE:0000020
messages
- UniProtKB P11215 ITGAM involved_in GO:1905114 GO_REF:0000024 ISS UniProtKB:P05555 P Integrin alpha-M ITGAM|CD11B|CR3A protein taxon:9606 20210428 ARUK-UCL occurs_in(CL:0000129),occurs_in(UBERON:0002479),occurs_in(UBERON:0009953)
- UniProtKB Q99572 P2RX7 involved_in GO:1905114 PMID:12151016 TAS P P2X purinoceptor 7 P2RX7 protein taxon:9606 20210428 ARUK-UCL occurs_in(CL:0000129),part_of(GO:0035585)
- ComplexPortal CPX-1062 abeta-40-42_human involved_in GO:1901216 PMID:7715705 IGI UniProtKB:P01580 P Amyloid-beta protein 40/42 complex beta-amyloid protein 40/42 heterodimer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterodimer|amyloid-beta-40/42 heterodimer|amyloid beta protein 40/42 heterodimer|beta-amyloid-40/42 heterodimer|beta amyloid protein 40/42 heterodimer|Abeta protein 40/42 complex|APP dimer protein_complex taxon:9606 20190426 ARUK-UCL occurs_in(CL:0000129),regulates_o_occurs_in(CL:0002609),occurs_in(UBERON:0000956)
- ComplexPortal CPX-1120 abeta-40-42-oligomer_human involved_in GO:0090647 PMID:25390368 TAS P Amyloid-beta protein 40/42 oligomeric complex fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0010942 PMID:22500019 IGI ComplexPortal:CPX-3187 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0010942 PMID:22500019 IGI UniProtKB:O60896,UniProtKB:P30988 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0010942 PMID:23386614 IGI UniProtKB:P04925 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170626 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0010942 PMID:23386614 IGI UniProtKB:Q07954 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170626 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0090647 PMID:11140685 IGI UniProtKB:P05067:PRO_0000000092 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170710 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0090647 PMID:16541076 TAS P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:0090647 PMID:25390368 TAS P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23164821 IGI UniProtKB:A0A0H2UHR3 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23164821 IGI UniProtKB:D3Z9J1 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23164821 IGI UniProtKB:P10909 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL occurs_in(GO:0005622),occurs_in(UBERON:0000956)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23164821 IGI UniProtKB:P12841 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170627 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23921129 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170622 ARUK-UCL occurs_in(CL:0002608),part_of(GO:1904646),regulates_o_occurs_in(CL:0002608)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1901216 PMID:23921129 IGI UniProtKB:P05067:PRO_0000000092 P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20170621 ARUK-UCL regulates_o_occurs_in(CL:0002609),part_of(GO:1904646)
- ComplexPortal CPX-1134 abeta-42-oligomer_human involved_in GO:1903207 PMID:21857966 IDA P Amyloid-beta protein 42 oligomeric complex pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex protein_complex taxon:9606 20171220 ARUK-UCL regulates_o_occurs_in(CL:0002609)
- ComplexPortal CPX-1826 intg_am_b2_human involved_in GO:1901216 GO_REF:0000024 ISS ComplexPortal:CPX-3129 P Integrin alphaM-beta2 complex alphambeta2 integrin complex|alpha-M/beta-2 integrin complex|ITGAM:ITGB2|Integrin MAC-1|CR3|Complement receptor 3|Macrophage 1 antigen|CD11b/CD18 protein_complex taxon:9606 20170710 ARUK-UCL regulates_o_occurs_in(CL:0000700),occurs_in(CL:0000243),part_of(GO:0033554)
- ComplexPortal CPX-3187 amy3-receptor_human involved_in GO:0010942 PMID:22500019 IGI ComplexPortal:CPX-1134 P Amylin receptor 3 complex Amylin receptor AMY3, CALCR/RAMP3|AMY3 complex|CALCR:RAMP3 protein_complex taxon:9606 20170628 ARUK-UCL
- ComplexPortal CPX-3187 amy3-receptor_human involved_in GO:0010942 PMID:22500019 IGI UniProtKB:P10997:PRO_0000004106 P Amylin receptor 3 complex Amylin receptor AMY3, CALCR/RAMP3|AMY3 complex|CALCR:RAMP3 protein_complex taxon:9606 20170524 ARUK-UCL regulates_expression_of(UniProtKB:P01100)
gorule-0000046
GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms
messages
- MGI MGI:97275 Myod1 enables GO:0042803 MGI:MGI:1934945|PMID:10652346 IPI UniProtKB:P10085 F myogenic differentiation 1 bHLHc1|MYF3|MyoD|Myod-1 protein_coding_gene taxon:10090 20230314 ARUK-UCL
- MGI MGI:894311 Pirb enables GO:0042803 MGI:MGI:5511064|PMID:24052308 IPI UniProtKB:P97484 F paired Ig-like receptor B Gp91|Lilrb3 protein_coding_gene taxon:10090 20230314 ARUK-UCL causally_upstream_of(GO:0001540)
- MGI MGI:1196458 Scarb2 enables GO:0042803 MGI:MGI:6112073|PMID:29199275 IPI UniProtKB:O35114 F scavenger receptor class B, member 2 9330185J12Rik|Cd36l2|LGP85|LIMP-2|LIMP II protein_coding_gene taxon:10090 20181031 ARUK-UCL
- UniProtKB P15172 MYOD1 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P10085 F Myoblast determination protein 1 MYOD1|BHLHC1|MYF3|MYOD protein taxon:9606 20230314 ARUK-UCL
- UniProtKB P05067 APP enables GO:0042803 PMID:15447668 IPI UniProtKB:P05067-PRO_0000000092 F Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP enables GO:0042803 PMID:15447668 IPI UniProtKB:P05067-PRO_0000000093 F Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP enables GO:0042803 PMID:18568035 IPI UniProtKB:P05067-PRO_0000000092 F Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20170213 ARUK-UCL UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP enables GO:0042803 PMID:22179788 IPI UniProtKB:P05067-PRO_0000000093 F Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP enables GO:0042803 PMID:23386614 IPI UniProtKB:P05067-PRO_0000000092 F Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0051260 PMID:15447668 IPI UniProtKB:P05067-PRO_0000000092 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000092
- UniProtKB P05067 APP involved_in GO:0051260 PMID:15447668 IPI UniProtKB:P05067-PRO_0000000093 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL has_input(UniProtKB:P05067-PRO_0000000093) UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP involved_in GO:0051260 PMID:18602473 IPI UniProtKB:P05067-PRO_0000000093 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL UniProtKB:P05067-PRO_0000000093
- UniProtKB P05067 APP involved_in GO:0051260 PMID:23386614 IPI UniProtKB:P05067-PRO_0000000092 P Amyloid-beta precursor protein APP|A4|AD1 protein taxon:9606 20230314 ARUK-UCL has_input(UniProtKB:P05067) UniProtKB:P05067-PRO_0000000092
- UniProtKB P10636 MAPT involved_in GO:0051260 PMID:26704708 IPI UniProtKB:P10636-8 P Microtubule-associated protein tau MAPT|MAPTL|MTBT1|TAU protein taxon:9606 20230314 ARUK-UCL happens_during(UBERON:0000112),happens_during(GO:0018105),occurs_in(UBERON:0002421),regulates(GO:0007611)|happens_during(UBERON:0018241),happens_during(GO:0018105),occurs_in(UBERON:0002421),regulates(GO:0007611) UniProtKB:P10636-8
gorule-0000061
GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050
messages
- RGD 61912 Slc6a6 is_active_in GO:0098797 PMID:29491210|RGD:21201269 IPI UniProtKB:Q9JJ19 C solute carrier family 6 member 6 gene taxon:10116 20200115 ARUK-UCL part_of(UBERON:0000955)
- RGD 708538 Nherf1 is_active_in GO:0098797 PMID:29491210|RGD:21201269 IPI UniProtKB:P31643 C NHERF family PDZ scaffold protein 1 gene taxon:10116 20200115 ARUK-UCL part_of(UBERON:0000955)
- UniProtKB O14745 NHERF1 is_active_in GO:0098797 GO_REF:0000024 ISS UniProtKB:Q9JJ19 C Na(+)/H(+) exchange regulatory cofactor NHE-RF1 NHERF1|NHERF|SLC9A3R1 protein taxon:9606 20200115 ARUK-UCL part_of(UBERON:0000955)
- UniProtKB P02649 APOE is_active_in GO:0034360 PMID:7683668 IDA C Apolipoprotein E APOE protein taxon:9606 20230531 ARUK-UCL
- UniProtKB P02649 APOE is_active_in GO:0034361 PMID:7683668 IDA C Apolipoprotein E APOE protein taxon:9606 20230531 ARUK-UCL
- UniProtKB P08047 SP1 is_active_in GO:0000791 PMID:14701757 IDA C Transcription factor Sp1 SP1|TSFP1 protein taxon:9606 20200204 ARUK-UCL
- UniProtKB P31641 SLC6A6 is_active_in GO:0098797 GO_REF:0000024 ISS UniProtKB:P31643 C Sodium- and chloride-dependent taurine transporter SLC6A6 protein taxon:9606 20200115 ARUK-UCL part_of(UBERON:0000955)
- UniProtKB P39656 DDOST is_active_in GO:0008250 PMID:22467853 IDA C Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST|KIAA0115|OST48|OK/SW-cl.45 protein taxon:9606 20200131 ARUK-UCL
- UniProtKB P46977 STT3A is_active_in GO:0008250 PMID:22467853 IDA C Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A STT3A|ITM1|TMC protein taxon:9606 20200131 ARUK-UCL
- UniProtKB P61803 DAD1 is_active_in GO:0008250 PMID:22467853 IDA C Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 DAD1 protein taxon:9606 20200131 ARUK-UCL
- UniProtKB Q13464 ROCK1 colocalizes_with GO:0106003 PMID:27853422 IDA C Rho-associated protein kinase 1 ROCK1 protein taxon:9606 20171206 ARUK-UCL part_of(UBERON:0000956)
- UniProtKB Q8N6L1 KRTCAP2 is_active_in GO:0008250 PMID:22467853 IDA C Keratinocyte-associated protein 2 KRTCAP2|KCP2 protein taxon:9606 20200131 ARUK-UCL
- UniProtKB Q8TCJ2 STT3B is_active_in GO:0008250 PMID:22467853 IDA C Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B STT3B|SIMP protein taxon:9606 20200131 ARUK-UCL